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Dr. Andrew Rynne
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Article Home Adult and Senior Health Sickle Cell Anemia

Sickle Cell Anemia

sickle-cell anemia is a inherited blood disorder presenting in childhood characterized by red blood cells which become abnormal, rigid, sickle shape decreasing the cells' flexibility due to the mutations in the hemoglobulin gene causing decreased oxygen carrying capacity


Sickle Cell Anemia is a childhood disorder which remains lifelong requiring frequent blood transfusions


  • Anemia and associated symptoms like fatigue and weakness
  • Episodes of pain in chest, abdomen, joints and bones
  • Swollen hands and feet may be the first signs of sickle cell anemia in babies.
  • Jaundice with yellowish discoloration of eyes
  • Frequent infections
  • Delayed growth and puberty
  • Vision problems




  • Dietary cyanate and thiocyanate, from foods containing cyanide derivatives, has been used as a treatment for sickle- cell anemia
  • Painful crises are treated symptomatically with analgesics, Opiods and NSAIDS
  • Folic acid and penicillin for controlling infections
  • Antibiotics, Simple blood transfusion and exchange transfusions
  • Hydroxyurea
  • Decreases the number and severity of attacks
  • Bone marrow transplants