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Dr. Andrew Rynne
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What causes fatigue, dry mouth, excessive thirst and sweating while on Thyronorm?

Answered by
Dr. Shehzad Topiwala


Practicing since :2001

Answered : 1663 Questions

Posted on Thu, 25 Aug 2016 in Thyroid Problem and Hormonal Problems
Question: I am female 35yr old .About one and half month back,I was feeling cramping pain in my lower limbs just like that of period pain alongwith whole body pain and weakness. My vitD3 level was 8.16 ng/ml on 18th XXXXXXX 2016.The doctor adviced me 3lac I. u vitD3 I. M and told me to take next dose after 3 months. At same time my T3, T4,TSH level were .85ng/ml,7.3micro g/dl,5.43microIU/ml.After about 15 days I start feeling radiating pain from pelvic region to above left knee.My doctor adviced USG which report was b/l mild dilatd pelvicalycealsystem (nonspecific? ).I was given 6 lac i.u vitD3 I. m and he told me to take 3 more doses of 6 lacI.mvit D3 at interval of 15days.The pain disappeared after one day of taking inj of vit D. After one and half month I again got myT3,T4,TSH level measured as1ng/ml,5.8 micro g/dl ,5.12microIU/ml on 27th july .For last 5 days , i started taking 12.5 mcg thyronorm daily on a doctor advice. I have no my own or any family history of hypothyroidism. Was this high TSH level was due to low vit D 3 level? Also please tell me does the radiating pain in my left thigh was due to vitD3 defiency? My Hb level is 12g/dl.Now today on 2nd Aug 2016,I again get vit D 3 level, free T3, free T4 and TSH level and calcium tested which results are as such 69.3 ng/ml, 4.92pmol/l, 9.25 pmol/l,5.34 micro IU/ml and calcium 9.4mg/dl.should .But during these 5days of taking 12.5mcg thyronorm, I started feeling much fatigue, dryness of mouth, excessive thirst and sweating without any obvious reason. 3 days back ,I have also caught cold and develop fever for which I took sninarest tab and ciprofloxacin 50mg.twice daily for 3 days. Should I stop taking thyronorm .?What should be my vitD3 maintenance dose?I rarely go outside without covering my face with clothes or without umbrella In sunlight. Also I don't want to expose myself to sunlight directly.
Answered by Dr. Shehzad Topiwala 36 minutes later
Brief Answer:

Detailed Answer:
Sorry to learn about your bothersome symptoms.

I generally do not prescribe thyronorm unless I am absolutely certain that hypothyroidism is permanent.

Vitamin D is not known to affect thyroid status and vice versa.
When I see someone like you in my practice, I typically order the following blood tests in addition to a detailed physical examination:

CBC (Complete Blood Count, also known as Hemogram; includes Hemoglobin, WBC and Platelet counts)
Electrolytes (Sodium and Potassium in particular)
HbA1c (Glycosylated Hemoglobin = your last 3 months' glucose average). Also known by other names such as GlycoHemoglobin or Glycated Hemoglobin or A1c
Liver function tests (SGOT , SGPT, Albumin, Bilirubin, Alkaline Phosphatase)
Kidney function tests (BUN, Creatinine)
TSH (checks your thyroid)
Free T4 (this too checks your thyroid) Thyroid autoantibodies : Anti Thyroid Peroxidase (TPO) antibodies and Anti Thyroglobulin antibodies
25 hydroxy Vitamin D levels (ideal range 40 to 60 ng/ml = 100 to 150 nmol/liter)

None of these tests require any fasting and can be done at any time of the day
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

The User accepted the expert's answer

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