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What Does My Blood Test Report Indicate?

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Posted on Tue, 12 Jul 2016
Question: Hi my brother age- 28 is suffering from sever loose motions from past 10 days, per day he has to goto bathroom minimum 5 to 6 times, he tried different tablets like Mahacef OZ, K stat, Buscopan, Providac capsules, Secnil forte from different doctors but motions are not controlled yet. According to him loose motion are in green in color & in the end blood is coming out from the anus.
Yesterday he has undergone some tests, reports are as follows
Stool Examination:
Color: Brownish, Consistency: Semi solid
Mucus: Present
Occult Blood: Positive
Reaction:Acidic
Others: Budding yeast cells present

Hemoglobin : 13.1
RBC Count: 6.05
M.C.V :71.1
M.C.H: 21.6
Total WBC count :12800
Basophils: 0.3
Smear Study: Leukocytosis, Erythrocytosis, RBC are normocytic to microcytic hypochromia
Doctor advised to go for Sonograph test tomorrow, but Im worried that It might be something related to cancer, please advice what might be the reason?
doctor
Answered by Dr. Tayyab Malik (1 hour later)
Brief Answer:
Patient is NOT suspicious for Cancer

Detailed Answer:
hi XXXXXXX

thank you for posting query@HCM.
noticed the detail history of the patient and viewed the reports. But i could not find the colonoscopy report.

a straightforward answer for your query related to cancer is: "at present, Cancer cause is Very UNLIKELY". however accurate diagnosis maybe made after doing scans and/or biopsy from intestine.

patient presented with "acute history"; so most likely the cause maybe due to inflammation(inflammatory bowel disease OR any rare infection). Did your brother travel to any tropical area last month?

Most likely, the endoscopist has taken biopsy sample during endoscopic examination of the intestine and the biopsy results may give a better picture of the underlying cause.

meanwhile,
consult your treating physician to stop the medications you mentioned EXCEPT Providac,
antidiarrheal medication maybe used like "loperamide" after discussing with treating physiccian
diet modification ( ingest food very low in "fiber" , ingest small meals and with no-to-less oil)
yogurt with every meal and ispagula husk maybe mixed in yogurt BUT without sugar
i would also advice to check ESR, CRP and Liver function test (all are blood test)

Health professionals aim to diagnose properly and manage patients according to their limited knowledge. Cure is blessed by the ONE who Created us, whose power and knowledge is unlimited .

Any further questions are welcomed.
If no further questions, kindly leave a review and close the dialogue box.

Wish the patient good and sound health.
thank you.
regards,
Dr Tayyab Malik
Above answer was peer-reviewed by : Dr. Raju A.T
doctor
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Follow up: Dr. Tayyab Malik (6 hours later)
Dear Doctor,

He didn't travel to any tropical area last month, just now we got colonoscopy reports (PFA)

At present doctor stopped giving food, so temporarily he stopped going for motions. These are the following medicines he is using.

1. Saccharomyces boulardii 250 mg
2. Mesalo foam ( for rectal use)
3. Emeset Injection
4. Sodium chloride injection
5. Pantoprazole for ijection / Troypan
6. Ceftriaxone injection

Leaving medications aside, I request you to explain the COLONOSCOPY report, as mentioned doctors have not found any active blood, so where does this blood coming from???

With all the reports I request you to explain the issue...
doctor
Answered by Dr. Tayyab Malik (2 hours later)
Brief Answer:
Biopsy results would give better picture.

Detailed Answer:
hi.
Thank you for getting back to me.

Gastroscopy (upper GI endoscopy) shows gastritis. Helicobacter pylori(hp) is a common cause for gastritis. if positive for Hp , eradication therapy is advised. Endoscopist did biopsy and results of biopsy are awaited.

Colonoscopy: showed multiple erosion(s) and small ulcer in the intestinal mucosa. However, in between the lesion, the mucosa appears Normal. So the lesion are NOT continuous and termed as "skip lesions". This maybe due to inflammatory bowel disease and/or colitis.
Biopsy results would aid in confirming the diagnosis.

Now answering your concern regarding active bleeding.
"active bleeding" was NOT observed during colonoscopic examination. It means the lesion was not bleeding during the colonoscopic procedure. As the patient is not eating anything, no episodes of diarrhea may have prevented active bleeding from lesions.
However, lesions may have bled in the past few days.

Bleeding from lesions in on and off and occult blood in stool(indicated in stool report) is difficult to observe with naked eye.

Now the biopsy results will give a better picture.

Hope to answer your any other concern.
Any further questions are welcomed.
If no further questions, kindly leave a review and close the dialogue box.

Wish the patient good and sound health.
Thank you.
Regards,
Dr Tayyab Malik
Above answer was peer-reviewed by : Dr. Sonia Raina
doctor
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Follow up: Dr. Tayyab Malik (3 hours later)
Your reply is informative, thanks. But I have another question to you...

As mentioned in the report, doctor has found few SUPERFICAL ULCERSs during colonoscopy & you have mentioned that there are small ulcer in the intestinal mucosa.

1. Main symptom of an ulcer is pain but my brother had never undergone into any of the symptoms like burning sensation in stomach, pain in abdomen or vomiting. why suddenly he will face all these issues without any symptoms?

2. SUPERFICAL ULCERSs are like next level of ulcers where it has affected another layer of COLON, so does it mean in future he may suffer with any other colon problems? if ulcers have grown to the next stage then what would you say about the age of ulcers ? did it start recently or he has ulcers form many years?

Kindly reply...


doctor
Answered by Dr. Tayyab Malik (3 hours later)
Brief Answer:
ulcer in colon maybe PainLess

Detailed Answer:
Hi.
It's a pleasure to answer your queries.

Gut wall layers from inside to outside...
Mucosa , then submucosa, then muscular layers and finally adventitia.

Firstly, to be more clear,and rephrasing my previous answer- "ulcer" is a lesion/break in the wall of intestine or stomach that extends beyond the mucosa...it maybe deep or superficial...
in the patient's case ; its superficial - most likely limited to submucosa and located in "colon" in discontinuous fashion.

Stomach ulcers may present with stomach pain/vomiting but the patient does NOT have stomach ulcers.

Now, intestinal(colon) ulcers, usually do NOT present with abdominal pain. The common symptoms are diarrhea +/- bleeding.

Colon ulcer are usually painless and get noticed when patient present with diarrhea +/- bleeding.
ulcer may have been developing in colon since quite a time but symptoms appeared in the past few days to couple of weeks.

Thirdly, most likely the medication(alongwith some diet modification) maybe given to combat the disease/ulcer in colon, once disease diagnosed after receiving biopsy results.

Hope to answer your any other concern.
Any further questions are welcomed.
If no further questions, kindly leave a review and close the dialogue box.

Wish the patient good and sound health.
Thank you.
Regards,
Dr Tayyab Malik
Above answer was peer-reviewed by : Dr. Arnab Banerjee
doctor
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Follow up: Dr. Tayyab Malik (10 hours later)
Dear Doctor,

As you know we all are waiting for BIOPSY reports from both colonoscopy and endoscopy, meanwhile doctor has performed sonography test & informed us the following

1. Cecum wall thickening

What is Cecum wall thickening? Is cecum wall thickening is because of IBD ? or what are the main causes for it? as suspected by doctor is my brother suffering from PANCOLITIS?? Is it dangerous? In reports, during colonoscopy doctors have mentioned that they could do colonoscopy only till Hepatic Flexure because of pain, if they could have done till CECUM we would have got to know about ulcers and other issues. How do we find issues with small intestine and Ascending part of colon?

2. Splenomegaly

Its shocking to hear about issues with spleen as well, how is speen related to our digestive system? Is blood flow is happening from spleen? How dangerous is splenomegaly in this condition with IBD

Can you please relate all these symptoms and reports that we have given it to you? We need your expert study.....

Thanks in advance





doctor
Answered by Dr. Tayyab Malik (2 hours later)
Brief Answer:
most likely Crohn Disease OR less likely any infectious disease

Detailed Answer:
hi.
thanks for getting back and sharing the ultrasonography report.
two findings:
1. "Caecum wall thickness" reflects inflammatory process at caecum.
2. Spleenomegaly; generally has many causes like malaria, typhoid, miliary TB, hemolytic anemias, lymphomas and leukemias.

in the patient's case, spleenomegaly maybe seen as "extraintestinal manifestation" of Crohn Disease OR any infectious disease (Typhoid/TB).

putting together:
most likely cause: Crohn disease ( IBD).
least likely cause is secondary to infectious diseases like tuberculosis, typhoid (enteric fever). Biopsy results will confirm.

"cancer is still very UNLIKELY".

and as the report mentioned, it might be difficult to pass the colonoscope beyond hepatic flexure due to pain. Secondly, if inflammation was active and passage of scope was NOT smooth though colon, endoscopist did not complete the procedure all the way to caecum forcefully, to "prevent bowel perforation".

however,if ithe cause is IBD or any infectious cause, the disease is treatable.

Health professionals aim to diagnose properly and manage patients according to their limited knowledge. Cure is blessed by the ONE who Created us, whose power and knowledge is unlimited .

Any further questions are welcomed.
If no further questions, kindly leave a review and close the dialogue box.

Wish the patient good and sound health.
thank you.
regards,
Dr Tayyab Malik
Above answer was peer-reviewed by : Dr. Yogesh D
doctor
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Follow up: Dr. Tayyab Malik (2 days later)
Dear Doctor,

Finally we have collected biopsy report of both colonoscopy and endoscopy (PFA). Kindly analyse the Biopsy report & explain us the biological terms & conclude the problem.

With this you have got all the pending reports & symptoms regarding my brothers issue, kindly let us know if its UC or IBD or some infection. What are the warning signs that we have to consider from the biopsy report? Please explain us everything for second opinion.
doctor
Answered by Dr. Tayyab Malik (13 hours later)
Brief Answer:
Mild Chronic Gastritis and acute flare of chronic colitis

Detailed Answer:
Hi.
thanks for uploading the biopsy results and getting back to me.

firstly, gastric biopsy only shows MILD CHRONIC GASTRITIS and the most common bug causing gastritis (Helicobacter pylori) was NOT seen.
mild chronic gastritis is "reversible". the treating physician may prescribe and antacid medication alongwith diet modification (decrease salt intake, avoid alcohol and spicy food).

secondly, the biopsy sample from colon does "NOT" show the histological features of Ulcerative colitis and/or Crohn's disease.
Therefore, chronic colitis is the diagnosis without knowing the cause. in may cases, cause of chronic colitis remains unknown.
superficial ulcer, edema and cells of "chronic inflammation" is observed in the tissue samples. It indicates that inflammation may have been commenced in the colon since long but the symptoms appeared in the past few weeks. The treating physician may prescribe medication to reduce the inflammation (anti-inflammatory drugs +/- steroids) and diet modification.
Food that is tolerant to the patient should only be ingested. ( usually dairy products, dry fruit, nuts are avoided).

As per now, the good news is that, there are NO RED FLAGS in the biopsy report.
the condition is Not severe and proper medication together with followup examination may help in improving quality of life.

Hope to answer your any other concern.
Any further questions are welcomed.
If no further questions, kindly leave a review and close the dialogue box.

Wish the patient good and sound health.
Thank you.
Regards,
Dr Tayyab Malik
Note: For further follow up on digestive issues share your reports here and Click here.

Above answer was peer-reviewed by : Dr. Veerisetty Shyamkumar
doctor
Answered by
Dr.
Dr. Tayyab Malik

Gastroenterologist

Practicing since :2009

Answered : 819 Questions

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What Does My Blood Test Report Indicate?

Brief Answer: Patient is NOT suspicious for Cancer Detailed Answer: hi XXXXXXX thank you for posting query@HCM. noticed the detail history of the patient and viewed the reports. But i could not find the colonoscopy report. a straightforward answer for your query related to cancer is: "at present, Cancer cause is Very UNLIKELY". however accurate diagnosis maybe made after doing scans and/or biopsy from intestine. patient presented with "acute history"; so most likely the cause maybe due to inflammation(inflammatory bowel disease OR any rare infection). Did your brother travel to any tropical area last month? Most likely, the endoscopist has taken biopsy sample during endoscopic examination of the intestine and the biopsy results may give a better picture of the underlying cause. meanwhile, consult your treating physician to stop the medications you mentioned EXCEPT Providac, antidiarrheal medication maybe used like "loperamide" after discussing with treating physiccian diet modification ( ingest food very low in "fiber" , ingest small meals and with no-to-less oil) yogurt with every meal and ispagula husk maybe mixed in yogurt BUT without sugar i would also advice to check ESR, CRP and Liver function test (all are blood test) Health professionals aim to diagnose properly and manage patients according to their limited knowledge. Cure is blessed by the ONE who Created us, whose power and knowledge is unlimited . Any further questions are welcomed. If no further questions, kindly leave a review and close the dialogue box. Wish the patient good and sound health. thank you. regards, Dr Tayyab Malik