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What Do These Following Blood Reports Indicate?

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Posted on Sat, 10 Sep 2016
Question: I have all classic hypo symptoms. Extreme fatigue, dry skin/scalp/nails. Cold feet, heat intolerance, diarrhea with constipation, purple nail beds with purple feet, tingling in extremities. Dizziness upon standing, chronic daily headaches, increased appetite, water retention, swollen and puffy face and ankles.
I am compound heterozygous on the 677t and 1289c for MTHFR. Can someone PLEASE help interpret these labs? Dr doesn't seem worried about thyroid.

First off CBC/Chem labs:
Alk/phos is Low at 54 (Optimal is 65-80)
CO2 is low at 22 (Optimal 24-28)
MCH is 32.1 (Optimal 28-32)
Lymphocytes are low at 19.7 (Optimal is 30-45)
Neutrophils are High at 7.2 (Optimal is 5-6)
Potassium is low at 3.4 (Optimal is 4.1-4.6)
RDW is 13.4 (Optimal is less than 13)
MCV is 94 (Optimal is 82-92)
Sodium is 142


Thyroid Levels
TSH 1.08
Total T4 7.3
T3Uptake 32
Free T3 3.1 (Optimal is above 3.2)
Free T4 1.46
Reverse T3 is 28.9 (Optimal is below 15)
TPO Antibodies 14 (Optimal below 15)
TGO Antibodies tested at .1 (Normaly we do not produce this antibody unless its needed.)
Both Antibody tests tested Negative accordingly to the lab, but there mere presence suggests something right?
Any help?
doctor
Answered by Dr. Mirjeta Guni (29 minutes later)
Brief Answer:
There are still exams needed.

Detailed Answer:
Hello,

Sorry to learn about your bothersome symptoms.
In medicine to give an appropriate conclusion and make a diagnosis the clinical evaluation is very important.

Anyway, i am trying to give some explanation to your lab results you described.

The thyroid is not the cause of the symptoms you described, even though they seem to be typically related to hypothyroidism. The hormonal results are those who make the diagnosis.

There are slight derangement in white blood cells, that suggest any infection, a urine sample would be of help.

The K level is low and if it is confirmed twice than some tests of adrenal gland function should be performed.

What i would suggest you to add to your exams would be the renal function test ( BUN, Creatinine), liver function tests (AST,ALT,GGT), Protein and albumine, Glucose level and Hba1c, Eritrosediment and Protein C reactive .
A careful clinical examination to evaluate the edema, blood pressure, cardiac function would be very helpful.
Hope the information will help.

Kind regards,
Dr.Mirjeta

Above answer was peer-reviewed by : Dr. Prasad
doctor
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Follow up: Dr. Mirjeta Guni (47 minutes later)
BUN- 17
Creatinine .7
AST/Sgot 24
ALT/SGPT 14
Total Protein 7.7
Albumin 4.7
Globulin 3.0

My blood pressure is typically around 110/69.
I had a recent EKG and ultrasound which found the mitral valve prolapse.
Cardiac funtion is normal. No one seems concerned about the edema either. Its not severe, but I am thin and its definitely noticeable to me.
From the Liver panel do you see any red flags?
Why is the Low T3/High Rt3 not concerning when there is clearly a T4 conversion issue going on?

My Alk/Phos levels were tested twice within 2 weeks and both times they were low. The first time was 60 the second time 54.
doctor
Answered by Dr. Mirjeta Guni (25 minutes later)
Brief Answer:
Welcome back.

Detailed Answer:
Welcome back!
I would not blame your thyroid as a cause of your symptoms as long as TSH, Ft4 and Ft3 are within the normal ranges (3.1 wouldn't be considered abnormal and would never cause such symptoms in these levels).
I do not see anything to worry in the liver and renal panel.
The low phosfatase alkaline is not suggestive of any proper pathology ( high levels are pathological) there are studies that reports a correlation between low ALP and vit D level.
So you may check the Vit D and if it is low it may explain the low ALP level.
Hope i have been clear.
Kind regards,
Dr.Mirjeta
Note: For further follow up on related General & Family Physician Click here.

Above answer was peer-reviewed by : Dr. Prasad
doctor
Answered by
Dr.
Dr. Mirjeta Guni

Endocrinologist

Practicing since :2006

Answered : 2414 Questions

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What Do These Following Blood Reports Indicate?

Brief Answer: There are still exams needed. Detailed Answer: Hello, Sorry to learn about your bothersome symptoms. In medicine to give an appropriate conclusion and make a diagnosis the clinical evaluation is very important. Anyway, i am trying to give some explanation to your lab results you described. The thyroid is not the cause of the symptoms you described, even though they seem to be typically related to hypothyroidism. The hormonal results are those who make the diagnosis. There are slight derangement in white blood cells, that suggest any infection, a urine sample would be of help. The K level is low and if it is confirmed twice than some tests of adrenal gland function should be performed. What i would suggest you to add to your exams would be the renal function test ( BUN, Creatinine), liver function tests (AST,ALT,GGT), Protein and albumine, Glucose level and Hba1c, Eritrosediment and Protein C reactive . A careful clinical examination to evaluate the edema, blood pressure, cardiac function would be very helpful. Hope the information will help. Kind regards, Dr.Mirjeta