Hello, I have recently been taking prednisone, started on 6 pills /day. I have been reducing med. by 1 a week, now down to 3/day. I am suffering from extreme sweeling of ankles abdomen, and face. My concern is that it IS pitted adema. I have shortness of breath. was prescribed this med due to diagnosed COPD. I am tired , larthargic and very heavy. I also have a sacral implant in my bladder. I have NEVER been a big person, I was very fit and slim. Now I have gained so much weight in little time that I don t know who is in the mirror. Please help me.