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Dr. Andrew Rynne
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Dr. Andrew Rynne

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Blood Test Shows Low Transferrin. Have Low Back Pain, Itchy Rash, Nausea, Weakness. Any Ideas?

Hi. I have low transferrin on my blood test for several months. I had low b12 last year and this is ok now but I've not been feeling best. When my b12 was low i became very weak and ended up needing spine tap which came back ok. I again have low back pain with an intensley itchy rash over the area of pain that comes and goes each few hours. With the lower back pain which has been severe last couple days, inc nausea and weak feeling in my backside and groin? Any ideas?
Fri, 6 Sep 2013
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Pathologist and Microbiologist,  's  Response
Hello and welcome to HCM,
Low transferrin levels indicate depletion of iron stores in body.
In this situation, the iron stores have to be replaced promptly else the symptoms of weakness, fatigue, palpitations, etc. appear.
Ferrous sulphate tablets have to be taken for atleast 3 months to replete the iron stores.
Low levels of vitamin B12 also leads to anemia but the mechanism of anemia is different.
Deficiency of vitamin B12 leads to neurological symptoms besides anemia.
Low back ache can be a manifestation of anemia.
However, low back ache is more commonly due to muscular strain and/or spinal canal stenosis or some other problem of the spinal cord.
Vitamin B12 deficiency does not lead to itchy skin lesion.
The itchy lesion can be due to skin lesion e.g. fungal infection.
However, clinical examination is required to make a diagnosis.
If the vitamin B12 levels are low, it has to be corrected by giving vitamin B 12 injections.

Thanks and take care
Dr Shailja P Wahal
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Blood Test Shows Low Transferrin. Have Low Back Pain, Itchy Rash, Nausea, Weakness. Any Ideas?

Hello and welcome to HCM, Low transferrin levels indicate depletion of iron stores in body. In this situation, the iron stores have to be replaced promptly else the symptoms of weakness, fatigue, palpitations, etc. appear. Ferrous sulphate tablets have to be taken for atleast 3 months to replete the iron stores. Low levels of vitamin B12 also leads to anemia but the mechanism of anemia is different. Deficiency of vitamin B12 leads to neurological symptoms besides anemia. Low back ache can be a manifestation of anemia. However, low back ache is more commonly due to muscular strain and/or spinal canal stenosis or some other problem of the spinal cord. Vitamin B12 deficiency does not lead to itchy skin lesion. The itchy lesion can be due to skin lesion e.g. fungal infection. However, clinical examination is required to make a diagnosis. If the vitamin B12 levels are low, it has to be corrected by giving vitamin B 12 injections. Thanks and take care Dr Shailja P Wahal