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What Does High LDH Value After Chemotherapy Indicate?

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Posted on Tue, 26 May 2015
Question: Dear Doctor,
I have recently finished a course of chemo for stage 2 lymphoma about a month ago. Doctors say I'm in remission and the cancer has only trace amounts left with the expectation it will go. But recently I'm finding I sweat a lot, I feel an itching in my body without a rash being present. And recently I've done a blood test with everything being within normal range except LDH being at 547, RBC being at 5.91 and MPV being at 6.7. So My LDH is above normal range, RBC is above normal range (slightly) and my MPV is below normal range. My apetite is good, I don't smoke any more (more than 4 months since I've been smoke free). Please help me shed some light on this.
Thank you
doctor
Answered by Dr. Indranil Ghosh (4 hours later)
Brief Answer:
this LDH may come down

Detailed Answer:
Hi

I understand your concerns. It is great news that the lymphoma has been controlled. Sometimes immediately after chemo LDH may be high because of high cell turnover and this comes down in 2-3 months. MPV is not something of concern and RBC will improve.

The symptoms may also be due to after effect of chemo and will subside slowly. Till then symptomatic treatment is appropriate.

As your scans are fine, I would not worry too much.

Hope this helps.
Regards
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Indranil Ghosh (4 hours later)
Dear Dr XXXXXXX

Thank you for your answer. Can you please tell me what I can do in regards to "symptomatic treatment"? Especially this itching around my body without an apparent sign of a rash or the itching subsiding. It feels like the itching is from the inside.
Thank you
Dawan
doctor
Answered by Dr. Indranil Ghosh (2 hours later)
Brief Answer:
Please refer below

Detailed Answer:
You can use local soothing creams like calamine and/or oral antihistaminics for itching. You need to consult your doc for the prescription of exact drug and dosage.

Regards
Note: For further queries related to kidney problems Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Indranil Ghosh

Oncologist

Practicing since :2004

Answered : 1712 Questions

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What Does High LDH Value After Chemotherapy Indicate?

Brief Answer: this LDH may come down Detailed Answer: Hi I understand your concerns. It is great news that the lymphoma has been controlled. Sometimes immediately after chemo LDH may be high because of high cell turnover and this comes down in 2-3 months. MPV is not something of concern and RBC will improve. The symptoms may also be due to after effect of chemo and will subside slowly. Till then symptomatic treatment is appropriate. As your scans are fine, I would not worry too much. Hope this helps. Regards