Brief Answer: Kindly go for investigations Detailed Answer: Hi, Welcome and thanks for posting your query to Healthcare magic. I can understand your concern for weight loss in your mother. After thorough reading of your mother's problem I can make out that she has lost a lot of weight in last 5 months. As per the medications - risperdal basically causes weight gain and can not cause any pigmentation. Smoking also do not cause such drastic weight loss. So in this case there has to be , though it can cause mild hyper-pigmentation. If I were her treating doctor then I would have gone for her complete blood count and serum biochemistry including X ray chest and sonography of abdomen to rule out any serious cause in her. I suggest you to go for the tests mentioned and report to me accordingly. Do take care of your mother. Dr Sanjay MD

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Brief Answer: You can wait for some days Detailed Answer: Hi, Welcome to the forum again and thanks for your further query. As the problem of weight loss and pigmentation is present form last few months so there is no acute need of urgent care. You can wait for some days of period and schedule an appointment with her primary care physician. Till that time I request you to kindly ask her to stop smoking at once. Give her the best nutritive diet you can with plenty of fruits, green leafy vegetables and sprouts to her. Do not worry she will be alright. With good health wishes, Dr Sanjay MD

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