Hello Cathy, I can understand your concern for the itching problem along with sarcodosis and a type 2 diabetes mellitus. You haven t told us your age and related history as since how long you have the itching and the other systemic complaints. There can be multiple causes of itching and a detailed history is required to help you better. Even then in my clinical experience both sarcodosis and a type 2 diabetes mellitus can cause itching problem. Hydroxyzine is a sedating antihistamine and is preferably to be taken at night time. In my patients with your kind of problem I prefer to give non-sedating antihistamine at day time. I give loratadine for 1-3 times depending on the severity of the itching. It is quite safe and do not interact with other drugs of you are taking. Hope it helps.