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Dr. Andrew Rynne
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Dr. Andrew Rynne

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Exp 50 years

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What Does Beta 2 Level At 9.9 And My Beta 1 Level At 7.4,indicate?

I have RA and my doctor has ran a battery of blood tests on me. One of which is a protein electrophoresis serium. My Beta 2 level is elevated it is a 9.9 and my Beta 1 level is high as well it is a 7.4. Just wondering what this could mean as I have an appt. with hematology/oncology on Monday at his request.
Tue, 1 Apr 2014
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Pathologist and Microbiologist,  's  Response
Hi!
Welcome to HCM!
Serum protein electrophoresis (SPEP) is a laboratory test that examines specific proteins in the blood .bLOOD SERUM is placed into a gel, or into liquid in a capillary tube, and exposed to an electric current to separate the serum protein components into five major fractions by size and electrical charge
-Albumin, Alpha-1, Alpha-2,BETA composed primarily of transferrin and C3 and Gamma, composed primarily of immunoglobulins.Transferrin and beta-lipoprotein (LDL) comprises the beta-1. Increased beta-1 protein due to the increased level of free transferrin is typical of iron deficiency anemia, pregnancy, and oestrogen therapy. Increased beta-1 protein due to LDL elevation occurs in hypercholesterolemia.
Beta-2 comprises C3 (Complement protein 3). It is raised in the acute phase response.may be due to rheumatoid arthritis.
you must get a complete blood count and iron study to rule out Iron def anemia and lipid profile.
hope this helps!
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What Does Beta 2 Level At 9.9 And My Beta 1 Level At 7.4,indicate?

Hi! Welcome to HCM! Serum protein electrophoresis (SPEP) is a laboratory test that examines specific proteins in the blood .bLOOD SERUM is placed into a gel, or into liquid in a capillary tube, and exposed to an electric current to separate the serum protein components into five major fractions by size and electrical charge -Albumin, Alpha-1, Alpha-2,BETA composed primarily of transferrin and C3 and Gamma, composed primarily of immunoglobulins.Transferrin and beta-lipoprotein (LDL) comprises the beta-1. Increased beta-1 protein due to the increased level of free transferrin is typical of iron deficiency anemia, pregnancy, and oestrogen therapy. Increased beta-1 protein due to LDL elevation occurs in hypercholesterolemia. Beta-2 comprises C3 (Complement protein 3). It is raised in the acute phase response.may be due to rheumatoid arthritis. you must get a complete blood count and iron study to rule out Iron def anemia and lipid profile. hope this helps!