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What Does This Blood Report Indicate?

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Posted on Wed, 8 Mar 2017
Question: My results indicate: MCV 0f 96, ALT of 41, Tyroid Peroxidase of 101, and Free T4 of .7. What do they mean?
YYYY@YYYY
doctor
Answered by Dr. Bonnie Berger-Durnbaugh (32 minutes later)
Brief Answer:
Information

Detailed Answer:
Hello,

Here is some information about your labs. Interpretation of labs should really be done in the context of your history and reason they were ordered as individual lab results do not always have a specific meaning in and of themselves.

MCV stands for mean corpuscular volume. In other words, the size of the red blood cells. Yours is very slightly high which may not mean much. Immature red blood cells are larger than mature ones, so there may be slightly more immature cells in your circulation. But at 96 I wouldn't worry about it.

ALT is alanine aminotransferase, a liver enzyme. Liver enzymes such as ALT can increase from alcohol use, or from medications. What happens is the liver cells (hepatocytes) become inflamed and spill out some of the enzymes they make. Yours is mildly elevated. If it were in the hundreds I would be concerned.

Thyroid Peroxidase Antibody elevation is a sign that your body is making antibodies against your thyroid tissue. This can go with autoimmune disorders of the thyroid (Hashimotos or Graves), but doesn't always. Again, a lab test in and of itself needs to be looked at in the context of your clinical symptoms and in the context of the other labs. Your thyroid function tests (Free T4, TSH) are fine. They might be fine because you are being treated with supplemental thyroid medication. However, if these labs were fine prior to starting thyroid medication, you may not need thyroid medication, but rather just have frequent rechecks. I would rely on the judgement of an endocrinologist to make that decision.

I hope this information helps. Please let me know if I can provide additional information.


Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Bonnie Berger-Durnbaugh (51 minutes later)
Dear Dr. XXXXXXX Berger-Durnbaugh,

Thank you for interpreting the results. I also received a result for Blood of 1 plus with an indication of AB

Urine appearance as 1 plus with an indication of AB
Pap test is AB- aglandular cell abnormality
My uterus lining is measuring 28

I am post menopausal. After 5 years, I bled lightly for a week and have been spotting lightly since. Prior to and currently, I am discharging alot to the point I discolor my underwear. Please advise.


doctor
Answered by Dr. Bonnie Berger-Durnbaugh (1 hour later)
Brief Answer:
Information

Detailed Answer:
A finding of atypical glandular cells on a Pap smear means that some of the cells from the cervix do not look normal. It is a lower level finding of abnormality (i.e. NOT at the stage of cancer at this time). However it does need to be followed up. Usually the next step is a colposcopy procedure. A colposcopy is an in-office procedure where the cervix is examined with a specialized scope and a small biopsy can be taken from the cervix.

Given that you are also having vaginal bleeding and are post-menopausal, an endometrial biopsy is needed too. This is also an in-office procedure. A very thin pipette is inserted through the cervical opening into the uterus. Inside the pipette is a small instrument that can take samples of tiny pieces of the uterine lining. These will be sent to pathology for examination. What you feel with an endometrial biopsy is a lot of cramping, because that's the uterus' response to being poked like that!

The 1+ blood seen in your urine needs to be followed up, but given you are having a bloody discharge from the vagina, it's possible this is a contamination - blood from the vagina rather than the urinary tract getting into the specimen. I recommend talking with your doctor about this. He or she should repeat the urine specimen and look into whether the bleeding is from the bladder or vagina.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Bonnie Berger-Durnbaugh (50 minutes later)
Will a D& C be necessary as well. I am not sure I am asking a dumb question. If fibroids are found should they be taken out all in one procedure. I am thinking it should be in a sec ond phase not the initial assessment. I am also afraid of the tools that will be used.

What questions should I be prepared with?

Thanks for your assistance.
XXXXXXX
doctor
Answered by Dr. Bonnie Berger-Durnbaugh (47 minutes later)
Brief Answer:
Information

Detailed Answer:
A D & C may not be necessary. The endometrial biopsy may be adequate to assess what is going on with the uterine lining. A D&C is a much more involved procedure than an endometrial biopsy.

Management of fibroids depends on the size and location of them. Usually fibroids are not so much of an issue after menopause, because they grow in response to hormones, and after menopause, they usually are smaller and less trouble. So if you did not have problems with fibroids before, it is unlikely that they are causing trouble now.

Regarding the endometrial biopsy, I had one done myself. There was menstrual like cramping, but I just focused on my breaths, and it didn't take long - the whole thing was done within 10 minutes. Afterwards, there was some lesser cramping for a few hours, and then back to normal. I didn't take pain medication, but taking ibuprofen (Advil) or naproxen would be reasonable.

Here is a video of what happens during an endometrial biopsy. As you can see, it involves a regular speculum, and then the thin pipelle.

https://www.youtube.com/watch?v=at-CfWUiClg

Regarding colposcopy, I have done this procedure on patients and they are not in a lot of pain. It is like a lengthy pelvic exam - takes 10 to 20 minutes.

And this is a video of colposcopy that shows all of the instruments that may be used: a regular speculum, a large Q-tip, vinegar solution (on the Q-tip), the colposcope (a special microscope which does NOT enter your body), and possibly an instrument that takes a small sample of the cervix (which is what causes the uterus to do some brief cramping). In the video, you will see that instrument when the doctor puts the sample in the specimen container.

https://www.youtube.com/watch?v=Xu2W1sSs6NE

You may not be able to just click to open these links. Instead, copy and paste them into your address bar to see the videos.

Questions you may want to ask:
when will you get back your results?
how will the staff notify you of your results and any follow up that may be necessary?

Note: For more information on hormonal imbalance symptoms or unmanaged diabetes with other comorbid conditions, get back to us & Consult with an Endocrinologist. Click here to book an appointment.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
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Dr. Bonnie Berger-Durnbaugh

General & Family Physician

Practicing since :1991

Answered : 3134 Questions

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What Does This Blood Report Indicate?

Brief Answer: Information Detailed Answer: Hello, Here is some information about your labs. Interpretation of labs should really be done in the context of your history and reason they were ordered as individual lab results do not always have a specific meaning in and of themselves. MCV stands for mean corpuscular volume. In other words, the size of the red blood cells. Yours is very slightly high which may not mean much. Immature red blood cells are larger than mature ones, so there may be slightly more immature cells in your circulation. But at 96 I wouldn't worry about it. ALT is alanine aminotransferase, a liver enzyme. Liver enzymes such as ALT can increase from alcohol use, or from medications. What happens is the liver cells (hepatocytes) become inflamed and spill out some of the enzymes they make. Yours is mildly elevated. If it were in the hundreds I would be concerned. Thyroid Peroxidase Antibody elevation is a sign that your body is making antibodies against your thyroid tissue. This can go with autoimmune disorders of the thyroid (Hashimotos or Graves), but doesn't always. Again, a lab test in and of itself needs to be looked at in the context of your clinical symptoms and in the context of the other labs. Your thyroid function tests (Free T4, TSH) are fine. They might be fine because you are being treated with supplemental thyroid medication. However, if these labs were fine prior to starting thyroid medication, you may not need thyroid medication, but rather just have frequent rechecks. I would rely on the judgement of an endocrinologist to make that decision. I hope this information helps. Please let me know if I can provide additional information.