Get your health question answered instantly from our pool of 18000+ doctors from over 80 specialties

177 Doctors Online
Doctor Image
Dr. Andrew Rynne

Family Physician

Exp 50 years

I will be looking into your question and guiding you through the process. Please write your question below.

What do these following VDRL and TPHA test reports indicate?

Answered by
Dr. Abhijit Sonawane

General & Family Physician

Practicing since :2011

Answered : 601 Questions

Posted on Fri, 6 Nov 2015 in General Health
Question: I detected sipilis with vdrl 1/32 and tpha 1/640 after 1 month ate antibiotics tested result is vdrl 1/16 and tpha 1/640. Why is tphs don't decrease?
Answered by Dr. Abhijit Sonawane 1 hour later
Brief Answer:
Because it shows presence of antibodies

Detailed Answer:
Thanks for posting in HCM.

VDRL and TPHA are tests for syphilis which are for veneral disease and treponema pallidum respectively.
VDRL will show the stage of infection and disease level in you body.
Whereas TPHA shows antibody formation in your body against treponema pallidum ie. agent causing syphilis.

As you have taken antibiotics course and so in response your VDRL levels have come down which indicates that treatment have worked and infection has one down.
now, TPHA levels at same titres 1/640 indicates that antibodies have formed and it will be positive for long time as it only shows that your blood has antibodies against syphilis.

So to decrease TPHA levels it will take longer time but it doesn't mean that you are still infected with syphilis. It just shows that you have been previously infected with syphilis and does not correlate with any active infection.

So do not worry as your VDRL levels have come down which suggest that treatment is working.

I hope I have answered your query well.
If you have any more query kindly write back to me.
Thank you
Above answer was peer-reviewed by : Dr. Vaishalee Punj
Follow up: Dr. Abhijit Sonawane 4 hours later
Thanks doctor for your reply, another questions :
o with VDRL 1/16, must I still take another antibiotics or penicilin injection?
o currently, my left eyes can't see clearly and the doctor said that my retina has swollen and this caused by stress. Is this also caused by sipilis?
o i am afraid that I also can suffer by HIV, what is the syndroms of this HIV?
Answered by Dr. Abhijit Sonawane 1 hour later
Brief Answer:
penicillin will be adequate. kindly read along

Detailed Answer:
Hello, thanks for following up with me.
There is a regimen for penicillin injections. IF there is fall in titres that means treatment with penicillin is working and it will advisable to complete the course as been given by your doctor.
So continue with penicillin injections.
Retinal swelling can be due to multiple reasons but yes one of the reasons is syphilis called as ocular syphilis but the findings in this condition is different from what your doctor saw that is retinal swelling. So both do not go along and what your doctor suspected the reason as stress might be correct.
HIV can be asymptomatic or it can come with symptoms like fever, malaise, weight loss, recurrent infections and other non specific complaints. If you want to be sure just get a HIV testing done from lab so as to be 100% sure that there is no HIV infection.
I hope I have answered your queries well.
I f you have any more questions kindly write back to me will be happy to help you.
Thank you
Above answer was peer-reviewed by : Dr. Vinay Bhardwaj

The User accepted the expert's answer

Share on
Question is related to
Diseases and Conditions ,   ,   ,  
Lab Tests
Medical Topics ,  

Recent questions on  Malaise

doctor1 MD

Hello, Since Monday i have been feeling sick, have a sore lower back, feel dizzy a lot of the time and have been crying a lot for no reason. I am due on my period this week i don t think i could be pregnant as i have been taking the pill . My periods usually are no cause for concern at all. I still have an appetite and have been eating well when the nausea settles down, it doesn t take long for it to come back though. Do you know what this could be? Should i go see a doctor? Thank you Becky

doctor1 MD

Hi, I am 43 female with prolactinomia (removed) SVT and hyatus hernia on half inderal 80 mg, omperazole 40mg and caberogoline 0. 5mg, i do suffer anxisety and i am in remission with agoraphobia but struggling my job leaves me sitting for 8 hours a day bored and my mind plays games... but I have been very sickly recently, stress is a factor, had a family crisis recently, but i have a lot of shoulder and neck pain and very fuzzy head and pressure in front of head. Ear feels blocked to right? Very nervous when out and about again. No appetite due to feeling sick and drinking not as much as I should so own worst enemy. Concerned I have cealics disease as very ill when at any white food! What do you advise please

doctor1 MD

I have been feeling sick for a while now. It happens mostly when i am driving or in the car, but i have never been car sick ever in my life. I feel like throwing up so i try to swallow my saliva to keep it down, but it get stuck on the gag reflex thing and it makes me feel like throwing up more. i tried eating before i go, i tried not eating before i go. i stopped taking a protein shake thinking that was the problem but that wasnt it.

doctor1 MD

Hello, i just got into bed and i am sitting half up (head propped up on pillows). I have been feeling sick for a few hours, but havent actually thrown up. I had a mild case of indigestion during the sickness feeling. two hours later and i still feel sick, and have started feeling dizzy, with my ears ringing and hurting alot!

doctor1 MD

Hello again doctor, I am having to write to you again due to a symptom that is bothering me from a week. I again had throat infection due to cool drinks and fever for 2 days. I only took paracetemol for 2 days and now I feel better. However, I am...

doctor1 MD

Can my symptoms be chemical burn on skin? I have itching bumps on legs and arms after swimming in pool inMexico ( walls of pool were being scrubbed in heated pool. I swam at other end ), then running on the beach in hot sun. It spreads, blisters,...

doctor1 MD

My daughter is 16 years old and since yesterday she presented with very high fever , abdominal pain and very painful muscles. Today her fever spiked again very high and she is still complaining of very painful muscles, abdominal pain and malaise ....