HealthCareMagic is now Ask A Doctor - 24x7 | https://www.askadoctor24x7.com

question-icon

What Causes Low Platelet Count In A Patient With Chronic Hepatitis C?

default
Posted on Tue, 5 May 2015
Question: I am 65 Female-I am having Hepatitis C. (detected 10 yrs ago)

Till now taken No Treatment-I fear Interferon. I am also a Brain AVM Patient.

My SGOT 35 SGPT 31. As because the AST/ALT RATIO IS 1.129, will it mean I am having Cirrohisis?

What SHOULD I DO NOW?

Serum Protein 6.9
albumin 4.2
globulin 2.7

Platelets 1,50,000
bilirubin 0.7 conjugated 0.5 unconjucated 0.2
Prothrombin Time 14 Sec
INR 1.0
doctor
Answered by Dr. Dr.P.Ratnakar Kini (6 hours later)
Brief Answer:
It is less likely that you have cirrhosis

Detailed Answer:
Hi,
Thanks for posting your query.
I am Dr.R.K and I am pleased to assist you.

Cirrhosis is not diagnosed by looking at the AST/ALT ratio.

Looking at the rest of the information you have provided, it is less likely that you have cirrhosis.
You albumin globulin ratio is more than one which is less likely if you have chronic liver disease like cirrhosis. In cirrhosis the ratio usually gets reversed.
The platelet count is at the lower limit of the normal range which is less likely if you have cirrhosis. In cirrhosis with its associated portal hypertension the platelet count is usually decreased.

Since you are chronic Hep C patient you are at the risk of development of cirrhosis of liver and liver cancer. Periodic follow up is essential.

Cirrhosis can be diagnosed with ultrasound scan/Fibroscan/Liver biopsy.
Liver cancer can be screened with ultrasound scan and serum alpha feto protein.

You need to get treated for Hep C.
Do not worry about Peg interferon.
Newer drugs have come which are more effective, less costly and with less side effects.

If you can tell which city you are from, I can guide you regarding the treatment for Hep C.

Regards,
Dr.R.K.
Above answer was peer-reviewed by : Dr. Neel Kudchadkar
doctor
default
Follow up: Dr. Dr.P.Ratnakar Kini (16 hours later)
Dear Doctor,

First of all, thanks a lot for stress relieving news.You dont know how much relief I got from your answer.

My husband had Hcv and we gave Pegasys+Ribavirin but his condition worsened and he died after a lot and lot of suffering.I think I got it from him.Thats why Interferon is a nightmare for me.

I am from XXXXXXX You have mentioned about more effective less costly and especially Less Side Effect Medicines.

Kindly inform me about the medicines.

Again thanks a lot.



doctor
Answered by Dr. Dr.P.Ratnakar Kini (4 hours later)
Brief Answer:
Sofosbuvir

Detailed Answer:
Hi,
Sofosbuvir is the new medication.

You can consult Dr XXXXXXX who is practising at SG Gastro Care at Saibaba Colony, XXXXXXX for the tests and treatment.

Regards,
Dr.R.K.
Note: For further follow up on digestive issues share your reports here and Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Dr.P.Ratnakar Kini

Gastroenterologist

Practicing since :1994

Answered : 2215 Questions

premium_optimized

The User accepted the expert's answer

Share on

Get personalised answers from verified doctor in minutes across 80+ specialties

159 Doctors Online

By proceeding, I accept the Terms and Conditions

HCM Blog Instant Access to Doctors
HCM Blog Questions Answered
HCM Blog Satisfaction
What Causes Low Platelet Count In A Patient With Chronic Hepatitis C?

Brief Answer: It is less likely that you have cirrhosis Detailed Answer: Hi, Thanks for posting your query. I am Dr.R.K and I am pleased to assist you. Cirrhosis is not diagnosed by looking at the AST/ALT ratio. Looking at the rest of the information you have provided, it is less likely that you have cirrhosis. You albumin globulin ratio is more than one which is less likely if you have chronic liver disease like cirrhosis. In cirrhosis the ratio usually gets reversed. The platelet count is at the lower limit of the normal range which is less likely if you have cirrhosis. In cirrhosis with its associated portal hypertension the platelet count is usually decreased. Since you are chronic Hep C patient you are at the risk of development of cirrhosis of liver and liver cancer. Periodic follow up is essential. Cirrhosis can be diagnosed with ultrasound scan/Fibroscan/Liver biopsy. Liver cancer can be screened with ultrasound scan and serum alpha feto protein. You need to get treated for Hep C. Do not worry about Peg interferon. Newer drugs have come which are more effective, less costly and with less side effects. If you can tell which city you are from, I can guide you regarding the treatment for Hep C. Regards, Dr.R.K.