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Taking Metformin. Pink Bleeding, Tired, No Concentration. Have PCOS. What Is Wrong With Me?

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Posted on Sun, 16 Sep 2012
Question: Hi my OBGYN has put me on metformin ER 50mg a day for the past 3 weeks. I was on normal metformin prior but the side effects were bad. My last period was on the 18/07/2012. I started what i thought was my period on the 23/05/2012 but it was more like a bright pink but only there when i wiped myself, it got to a small mild period. They were gone by sunday the 26/08/2012. My periods are normally quite a heavy flow. Now im just so tired (exhausted) moody want to sleep and have no concentration skills at all. I was diagnosed with PCOS a few years ago. I just dont know whats wrong with me!!
doctor
Answered by Dr. Dr. Chandra Shekhar Sharma (1 hour later)
Hi,

Welcome to XXXXXXX

Metformin is an anti-diabetic drug. Women suffering with PCOS, generally have insulin resistance, thus metformin was prescribed to you.

Menstrual period generally starts on 14th day of ovulation. But in women with PCOS, ovulation is suppressed. Menstrual cycles becomes irregular, bleeding during period is sometimes heavy and other times light also.

Very light/spotty bleeding pinkish/brownish in color, can occur due to implantation also. But bleeding due to implantation generally doesn't continue for 3 days.
Your symptoms can be due to hormonal irregularity.

Metformin can improve your fertility by reversing endocrine abnormality and improving your ovulatory response.

If the bleeding was in the form of spots only, you can get pregnancy tested after a week.

Thanks for trusting XXXXXXX and posting your query.

Hope you found my response to your query informative and helpful.

If you have further concerns in this regard, I would be happy to discuss those with you as well.

With good wishes,

Dr.Chandra Shekhar Sharma

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Dr. Chandra Shekhar Sharma (14 hours later)
Thank you the response was great. My next question is why an opk test says that i am ovulating however when we have had sex nothing seems to happen. My husband has had a motility test done and he has a normal count. The OBGYN said that i may not have any mature eggs. How long should it be before the metformin starts to help with the improvement and maturity of my eggs. We have been ttc now for over 12 months and had 3 cycles of clomid. I know i shouldnt but its hard when my friends are all conceiving around me.
Thank you the response was great. My next question is why an opk test says that i am ovulating however when we have had sex nothing seems to happen. My husband has had a motility test done and he has a normal count. The OBGYN said that i may not have any mature eggs. How long should it be before the metformin starts to help with the improvement and maturity of my eggs. We have been ttc now for over 12 months and had 3 cycles of clomid. I know i shouldnt but its hard when my friends are all conceiving around me.
doctor
Answered by Dr. Dr. Chandra Shekhar Sharma (4 hours later)
Hi,

Welcome again,

OPK test detects Luteinizing Hormone (LH) surge only. Normally ovulation occurs within 24-48 hours of LH surge. In case of PCOS, ovulation may not follow LH surge.

You can prepare a Basal body temperature rise by 0.4-0.8 F on day of ovulation and remain same during remaining part of menstrual cycle.

To identify day of ovulation, you can use cervical mucus detection method also.

Cervix raises to slightly higher position just before & during ovulation.

"How much time Metformin will take" vary from patient to patient.

Clomiphen is used to stimulate ovulation. If clomiphen doesn't work, a new anti-estrogen called Letrozole can be used.

Clomifen resistant women suffering with PCOD, may need HMG(gonadotrophin) to induce ovulation.

Difficult patients may require a combination of GnRH analog and HMG to induce ovulation successfully.

Low doses of dexamethasone can be given simultaneously to suppress androgen production from adrenal gland.

With good wishes,
Note: Revert back with your gynae reports to get a clear medical analysis by our expert Gynecologic Oncologist. Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Dr. Chandra Shekhar Sharma

General & Family Physician

Practicing since :1979

Answered : 622 Questions

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Taking Metformin. Pink Bleeding, Tired, No Concentration. Have PCOS. What Is Wrong With Me?

Hi,

Welcome to XXXXXXX

Metformin is an anti-diabetic drug. Women suffering with PCOS, generally have insulin resistance, thus metformin was prescribed to you.

Menstrual period generally starts on 14th day of ovulation. But in women with PCOS, ovulation is suppressed. Menstrual cycles becomes irregular, bleeding during period is sometimes heavy and other times light also.

Very light/spotty bleeding pinkish/brownish in color, can occur due to implantation also. But bleeding due to implantation generally doesn't continue for 3 days.
Your symptoms can be due to hormonal irregularity.

Metformin can improve your fertility by reversing endocrine abnormality and improving your ovulatory response.

If the bleeding was in the form of spots only, you can get pregnancy tested after a week.

Thanks for trusting XXXXXXX and posting your query.

Hope you found my response to your query informative and helpful.

If you have further concerns in this regard, I would be happy to discuss those with you as well.

With good wishes,

Dr.Chandra Shekhar Sharma