Sign-in to Ask A Doctor - 24x7
OR
Sign in with Google
Suggest Treatment For Carcinoma In Situ
Question: Is it possible to have a negative pap smear for 20 years and then the 21st year have CIN III dysplasia (carcinoma in situ)? HSIL and high-risk HPV. I have heard that this is a very slow growing process. Why/how would that dramatic change happen in one year? Does it mean there is a higher risk of it becoming invasive cancer due to the rapid change in one year?
Brief Answer:
HAPPENS SOMETIMES, DOES NOT MEAN FAST CANCER TOO
Detailed Answer:
Hello
Thanks for writing to us with your health concern.
What you mention is actually commoner than you think , while not the norm.
Basically the virus has a high rate of dormancy, and in some people, it takes years for the cervical changes to evolve, going from a less severe to more severe pattern over years.
In some, maybe less than 10 %, this transition occurs fairly rapidly.
Factors such as your immunity, stress, peri menopause etc can play a role in flaring up the latent infection.
In that scenario, the cervical lesions undergo the whole gamut of changes from normal to CIN 3 pretty fast , as in your case, over a year.
However in no way does that imply that you would equally have a radical invasive cancer in a year.
Cancerous changes are a different spectrum from CIN, and as long as CIN 3 is adequately and promptly treated, there is absolutely no reason for malignant changes to occur at all, forget drastically.
Of course, boosting your immunity ( good workouts, regular and sufficient sleep, healthy eating, yoga, meditation ) is always a good cue to follow.
Hope this helped you.
Wish you luck.
Please feel free to discuss further.
HAPPENS SOMETIMES, DOES NOT MEAN FAST CANCER TOO
Detailed Answer:
Hello
Thanks for writing to us with your health concern.
What you mention is actually commoner than you think , while not the norm.
Basically the virus has a high rate of dormancy, and in some people, it takes years for the cervical changes to evolve, going from a less severe to more severe pattern over years.
In some, maybe less than 10 %, this transition occurs fairly rapidly.
Factors such as your immunity, stress, peri menopause etc can play a role in flaring up the latent infection.
In that scenario, the cervical lesions undergo the whole gamut of changes from normal to CIN 3 pretty fast , as in your case, over a year.
However in no way does that imply that you would equally have a radical invasive cancer in a year.
Cancerous changes are a different spectrum from CIN, and as long as CIN 3 is adequately and promptly treated, there is absolutely no reason for malignant changes to occur at all, forget drastically.
Of course, boosting your immunity ( good workouts, regular and sufficient sleep, healthy eating, yoga, meditation ) is always a good cue to follow.
Hope this helped you.
Wish you luck.
Please feel free to discuss further.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
When you say treated adequately and promptly, would you waiting for a month after biopsies and colposcopy to receive a LEEP procedure still be able to consider it to be promptly?
Brief Answer:
WITHIN A WEEK IS BEST.
Detailed Answer:
While it is not prompt, it is not too late.
I would have done it within a week.
Take care.
WITHIN A WEEK IS BEST.
Detailed Answer:
While it is not prompt, it is not too late.
I would have done it within a week.
Take care.
Note: Revert back with your gynae reports to get a clear medical analysis by our expert Gynecologic Oncologist. Click here.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Answered by
Get personalised answers from verified doctor in minutes across 80+ specialties
