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Suggest Remedies For Severe Breathing Trouble While Taking Antibiotics

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Posted on Sat, 10 Dec 2016
Question: I have bronchitis, taking antibiotic: amox-clav 875-125mg ev 12 hrs + taking tussin DM (dextromethorphan HBr USP 20 mg ev 4-5 hrs, + on nebulizer (albuterol sulfate) ev 4-5 hrs which usually works, but last 2 times on the nebulizer, my asthma got worse/ shorter breaths & my inhaler (Advair, which usually works if the albuterol inhaler doesn't, didn't help. It took an hour to get breathing back to almost normal, and straight black coffee finally helped. I normally take Wellbutrin sr150& losartan potassium 100 mg,& cartia XT 300 for BP & mild anxiety daily, + levothyroxine112 mcg, omneprazole dr40 mg, atorvastatin 40 mg daily. I've had the augmenten before without this breathing problem, the cough syrup is a new generic brand, not Robutussen. What is causing the added breathing problem this time?
doctor
Answered by Dr. Drkaushal85 (8 hours later)
Brief Answer:
Infection is the most common cause for acute worsening.

Detailed Answer:
Thanks for your question on Healthcare Magic.
I can understand your concern.
Infection is the most common cause for this kind acute worsening.
And combination of amoxicillin and clavulinic acid is not always sufficient to counteract infection.
You need additional coverage in the form of gram negative and anaerobic bacteria.
So you can switch to levofloxacin and clindamycin.
Another reason is more inflammation. And so oral short course of steroid is also needed.
Hope I have solved your query. I will be happy to help you further. Wish you good health. Thanks.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Drkaushal85 (37 hours later)
Thanks for the detailed answer- very much!
My Dr. wants to keep me on this antibiotic which is causing diarrhea (not spft stool, but all liquid) thru Friday (tomorrow) at the earliest . I started it on Sunday evening 5 PM, so that's about 5 days of misery. She thinks it may not have had enough time to work. Last time I took "Augmenten" , it didn't cause diarrhea, and the infection started in the sinus with a sinus infection. I didn't think this antibiotic would be strong enough, and told the prescribing , on-call partner-Dr. Sunday this, but he pre-scribed it anyway- or at least this "Amox-Clav" version. I know what he gave me is the generic, but are all "augmenten" varieties the same? and do you think I should stay on it with the diarrhea? even if I suggest adding the levoflaxin and clindamycin? You do mean adding both-right? Do they have side common effects I should be aware of? (as my Dr. said the diarrhea was common with the one I am on now.) Which steroid would you recommend, specifically? I quit the nebulizer (albuterol sulfate inhaler) when it caused increased heart beat & quicker, shorter breaths, that took an hour & 2 cups of black coffee to stop(the home remedy, my former dr. told me helped when the advair or albuterol wasn't. ) Pill steroids usually do not exacerbate my asthma. That shouldn't hurt my BP too badly though, remembering I am on 2 meds for high BP regularly. Thank you Dr. Bhavsar sooooo much!
doctor
Answered by Dr. Drkaushal85 (12 hours later)
Brief Answer:
You should take deflazacort.

Detailed Answer:
Thanks for your follow up question on Healthcare Magic.
I can understand your concern.
First of all sorry for late reply as I was busy. And no need to worry as I got your follow up question as it is.
Augmentin is known to cause diarrhea. You can take probiotic drug like sporolac for prevention of diarrhoea. You can also eat more of yogurt, curd and buttermilk as these are rich in lactobacillus.
Generic formulations of amoxicillin plus clavulinic acid are causing more diarrhoea as compare to standard formulations (personal experience).
Either you start levofloxacin and clindamycin combination or Augmentin and clindamycin combination.
If diarrhoea is more and troublesome, you can shift to levofloxacin and clindamycin combination.
And for steroid, you should take newer molecule (deflazacort).
Deflazacort is safe in cardiac, diabetic, hypertensive and osteoporotic patients. So it is good for you.
Hope I have solved your query. I will be happy to help you further. Wish you good health. Thanks.
Above answer was peer-reviewed by : Dr. Nagamani Ng
doctor
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Follow up: Dr. Drkaushal85 (36 hours later)
Thanks for the detailed answer. My DR changed me to levofloxacin 500mg/dy,(off the generic augmenten) and gave me a methy1prednisone 4 mg dosepk- both are helping, coughing way down, sleeping 4 -5 hrs straight last night, with some residual diarrhea , but continue to eat 1 serving of yogurt per day- 1/2 in am, 1/2 in afternoon, still not much appetite with all the liquid I am drinking steadily. I may try the sporolac if diarrhea persists past Sat/today. Do you still think I need the clindamycin? (Dr. wasn't happy with me suggesting another antibiotic, so any argument (words on that behalf) would help.) Should I still ask for the deflaacort? given the steroid sh6e gave me. I value your opinion, & will fight for it (in a nice way, with my Dr., if you think I should?)
Also, I forgot to ask before, how much guaifenesin per day & the frequency, you'd recommend for helping to dilute the mucus in my chest - knowing I cannot tolerate usually more than 800-1000mg/dy= about 2 Musinex pills, 1 every 12 hrs. I suffered from dehydration with all the special cough syrup (400mg ev 4 hrs) she had me on at first- that now, I am only taking once ev 12 hrs now, with a 200 mg guaifenein cough syrup that contains no dextromethorphan every 12 hrs...a bit more guaifenesin than usual for me, but I am managing OK without the dry mouth, frequent dry cough, mild headache, & muscle cramps the former special syrup taken too frequently caused. Thanks - more than you know! I am sooo thankful to be feeling better! hopefully, able to be back at work next week! (Sick of being sick!) sincerely, XXXXXXX
doctor
Answered by Dr. Drkaushal85 (19 hours later)
Brief Answer:
Levofloxacin alone is also better.

Detailed Answer:
Thanks for your follow up question on Healthcare Magic.
I can understand your concern.
First of all sorry for late reply as I was busy in weekend.
Well, levofloxacin alone is also better. I don't think it will cause diarrhea.
Deflazacort is newer steroid which is devoid of many side effects. So you can argue with your doctor if he/she wants to give you for long time.
For 1 month, methyprednisolone is ok. But if you are taking for more than 1 months then deflazacort is better.
I don't know the exact dose of guaphenesin but with standard cough expectorant syrup formula containing guaphenesin, you can take it 1 tea spoon full twice daily safely without any side effects.
Hope I have solved your query. I will be happy to help you further. Wish you good health. Thanks.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Drkaushal85 (4 hours later)
Much better in just 1 more day! The steroid is only for 5 dys XXXXXXX -and as it is working, that should do. Your help & expertise is much appreciated! Thanks for the time to answer my questions! Very much! God bless you! and your work! XXXXXXX
doctor
Answered by Dr. Drkaushal85 (50 minutes later)
Brief Answer:
Thanks for your kind words.

Detailed Answer:
Thanks for your follow up question on Healthcare Magic.
Thanks for your kind words. It's always encouraging for doctors to hear positive feedback from patients. Thanks a lot.
Hope I have solved your query. If you are not having further queries, then please close the conversation and rate my answer.
You can ask me directly on bit.ly/askdrkaushalbhavsar. Wish you good health. Thanks.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Dr. Drkaushal85

Pulmonologist

Practicing since :2008

Answered : 15005 Questions

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Suggest Remedies For Severe Breathing Trouble While Taking Antibiotics

Brief Answer: Infection is the most common cause for acute worsening. Detailed Answer: Thanks for your question on Healthcare Magic. I can understand your concern. Infection is the most common cause for this kind acute worsening. And combination of amoxicillin and clavulinic acid is not always sufficient to counteract infection. You need additional coverage in the form of gram negative and anaerobic bacteria. So you can switch to levofloxacin and clindamycin. Another reason is more inflammation. And so oral short course of steroid is also needed. Hope I have solved your query. I will be happy to help you further. Wish you good health. Thanks.