Is MRI a confirmatory test for multiple sclerosis?
MRI could give additional information, nerve conduction study needed too.
Hello and thanks for using HCM.
I have read your question and understand your concerns.
Multiple sclerosis is a very rare condition to be found at that age, moreover fatigue and legs weakness could be related to a number of other conditions besides MS.
Since ANA is found positive, and elevated sedimentation rate, autoimmune diseases should be considered and evaluated further, including lupus.
In my opinion, peripheral neuropathy caused both by diabetes and/or Epstein-Barr, should be considered as a possible cause of fatigue and legs weakness.
A spinal cord and brain MRI could give additional information about involvement of central nervous system or not, and could confirm/exclude MS, but nerve conduction study and evoked potentials should be done too, to evaluate peripheral nervous system status too.
Hope you found the answer helpful.
Let me know if I can assist you further.
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