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How To Increase Blood Platelet Count?
Question: how to increase blood platelet when its very low 20000 or less. hemohlobin is also very low 6.4. doctor tried put 16 bottel platlet and 12 bottle blood.
let me know how yo make patient better.
let me know how yo make patient better.
Brief Answer:
HLA matched or single. donor platelets
Detailed Answer:
Hi,
Thanks for asking.
I am Dr. Prakash HM and I will be answering your query.
Based on your query, my opinion is as follows:
1. Single donor platelet transfusion, every two days, three times should be helpful. Each exchange will increase by 10-15000, leading to 50-60000 count within a week. Pooled donor platelets can cause immune reactions due to multiple antibodies, which can cause platelet refractoriness.
2. Still better would be HLA matched platelets.
3. RBC packed cells can be given. For 6.4g%, unless there is any complications, no further transfusion necessary.
4. Nutritional supplements with b12 and folic acid is necessary.
5. Need to watch for any internal bleeding. When the count falls less than 10000, risk increases of internal bleeding.
Hope it helps.
Any further queries, happy to help again.
Dr. Prakash HM
HLA matched or single. donor platelets
Detailed Answer:
Hi,
Thanks for asking.
I am Dr. Prakash HM and I will be answering your query.
Based on your query, my opinion is as follows:
1. Single donor platelet transfusion, every two days, three times should be helpful. Each exchange will increase by 10-15000, leading to 50-60000 count within a week. Pooled donor platelets can cause immune reactions due to multiple antibodies, which can cause platelet refractoriness.
2. Still better would be HLA matched platelets.
3. RBC packed cells can be given. For 6.4g%, unless there is any complications, no further transfusion necessary.
4. Nutritional supplements with b12 and folic acid is necessary.
5. Need to watch for any internal bleeding. When the count falls less than 10000, risk increases of internal bleeding.
Hope it helps.
Any further queries, happy to help again.
Dr. Prakash HM
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
yes the patient have upper GI bleeding and doctor don't want ti operates until platelets count reach to 50k or more. let me know how should approach to tell current doctors. do you know any good doctor or hospital in XXXXXXX which can treat this sitution.
Brief Answer:
single donor apheresis platelet - best
Detailed Answer:
Hi,
Thanks for asking again.
Risk of bleeding increases during invasive investigation.
Improvement can be done through evaluation of immune antibodies via lymphocytotoxicity test or platelet antibodies evaluation or even platelet crossmatching. Most of the setup with dedicated transplant unit or transfusion medicine department in all major setups should have this.
If not platelet apheresis from single donor can be used to raise platelet count. Single donor platelet can be collected up to 3 times in a week.
Discuss with your doctor regarding single donor platelet or immune antibodies evaluation.
Hope it helps.
Any further queries, happy to help again.
Dr. Prakash HM
single donor apheresis platelet - best
Detailed Answer:
Hi,
Thanks for asking again.
Risk of bleeding increases during invasive investigation.
Improvement can be done through evaluation of immune antibodies via lymphocytotoxicity test or platelet antibodies evaluation or even platelet crossmatching. Most of the setup with dedicated transplant unit or transfusion medicine department in all major setups should have this.
If not platelet apheresis from single donor can be used to raise platelet count. Single donor platelet can be collected up to 3 times in a week.
Discuss with your doctor regarding single donor platelet or immune antibodies evaluation.
Hope it helps.
Any further queries, happy to help again.
Dr. Prakash HM
Note: Do you have more questions on diagnosis or treatment of blood disorders? Ask An Expert/ Specialist Now
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
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