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Do ACE Inhibitors Affect The Creatinine Level In The Body?

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Posted on Wed, 19 Jul 2017
Question: can ace inhibibors affect the creatinine level in the body?
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Answered by Dr. Panagiotis Zografakis (2 days later)
Brief Answer:
they may raise it

Detailed Answer:
Hello,

ace inhibitors will usually raise the creatinine levels a bit. In most patients this is not significant. In patients with renal arterial stenosis (particularly when it's bilateral) using ace inhibitors may raise the creatinine levels significantly and cause acute renal failure. These effects usually occur soon after initiation of treatment (within a week or so) but may later as well.

If you have chronic kidney disease then you'd better stick to your nephrologist's advice. The nephrologists know the effects of drugs on the kidneys and will suggest the best treatment for your case. Despite the untoward renal effects of ace inhibitors in some patients, they're beneficial in other patients with renal disease, so the decision to use (or avoid) this drug should be left to the treating physician who knows your medical history.

I hope you find my comments helpful!
Kind Regards!
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Panagiotis Zografakis

Internal Medicine Specialist

Practicing since :1999

Answered : 3810 Questions

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Do ACE Inhibitors Affect The Creatinine Level In The Body?

Brief Answer: they may raise it Detailed Answer: Hello, ace inhibitors will usually raise the creatinine levels a bit. In most patients this is not significant. In patients with renal arterial stenosis (particularly when it's bilateral) using ace inhibitors may raise the creatinine levels significantly and cause acute renal failure. These effects usually occur soon after initiation of treatment (within a week or so) but may later as well. If you have chronic kidney disease then you'd better stick to your nephrologist's advice. The nephrologists know the effects of drugs on the kidneys and will suggest the best treatment for your case. Despite the untoward renal effects of ace inhibitors in some patients, they're beneficial in other patients with renal disease, so the decision to use (or avoid) this drug should be left to the treating physician who knows your medical history. I hope you find my comments helpful! Kind Regards!