Sign-in to Ask A Doctor - 24x7
OR
Sign in with GoogleGet your health question answered instantly from our pool of 18000+ doctors from over 80 specialties
What Does Large Areas Of Hyalinizing Necrosis And Granulomas Indicate?
lung biopsy of nodual. Initial: showing large areas of hyalinizing necrosis and granulomas, no malignancy noted. Special stains results: done with stains for AFB, Pas and GMS performed. no definite fungal organisms identified though very rare cocci sugested for fungi are identified on the pas stain. Clinical correlation is reccommended. What does this mean?
Sat, 24 May 2014
Hello and welcome to HCM,
The interpretation of biopsy report is as follows:
Presence of necrosis and granulomas suggests presence of chronic granulomatous inflammations.
Granulomatous inflammations include tuberculosis, sarcoidosis, tuberculosis, fungal infections, berylliosis etc.
Special stains are required to identify the causative organism.
ZN stain is done for tuberculosis or AFB.
PAS stain is done for fungus and PAS stain is showing presence of fungi.
Thus, a possibility of fungal infection is suggested.
The histopathological examination has to be coupled with clinical assessment for diagnosis.
Thanks and take care
Dr Shailja P Wahal
The interpretation of biopsy report is as follows:
Presence of necrosis and granulomas suggests presence of chronic granulomatous inflammations.
Granulomatous inflammations include tuberculosis, sarcoidosis, tuberculosis, fungal infections, berylliosis etc.
Special stains are required to identify the causative organism.
ZN stain is done for tuberculosis or AFB.
PAS stain is done for fungus and PAS stain is showing presence of fungi.
Thus, a possibility of fungal infection is suggested.
The histopathological examination has to be coupled with clinical assessment for diagnosis.
Thanks and take care
Dr Shailja P Wahal
I find this answer helpful
Disclaimer: These answers are for your information only and not intended to replace your relationship with your treating physician.
This is a short, free answer.
For a more detailed, immediate answer, try our premium service
[Sample answer]
Related questions you may be interested in
Recent questions on Biopsy
Loading Online Doctors....