Hi, Silver sulfadiazine cream is commonly used to treat burns and prevent or treat infection. While it is generally considered safe and effective, like any medication, it can have potential side effects. Some possible side effects of silver sulfadiazine cream include: * Skin reactions: It is possible to experience skin irritation, redness, itching, or a burning sensation at the application site. This is usually mild and temporary. * Allergic reactions: Some individuals may be allergic to silver sulfadiazine. Allergic reactions can manifest as skin rash, hives, swelling, difficulty breathing, or dizziness. If you experience any of these symptoms, discontinue use and seek medical attention immediately. * Blood disorders: In rare cases, silver sulfadiazine can affect the production of blood cells, leading to blood disorders. Signs of a blood disorder may include unexplained bruising or bleeding, persistent sore throat, or general weakness. * Regarding the healing process and the use of other products, it s important to follow the guidance of your healthcare provider. They will be able to assess the severity of your burns and determine the appropriate treatment plan, including when and if alternative products can be incorporated. Depending on the extent of the burns, you may or may not require a skin graft. If you have concerns or questions about your treatment, it s best to consult with your healthcare provider for personalized advice. Take care. Hope I have answered your question. If you require a personalized response, kindly use the Ask A Doctor service and post a follow-up query. Regards, Dr. Priyanka, General & Family Physician