hi, thanks for your query, Mononucleosis is associated with fatigue that can last up to several months. Symptoms are not usually felt until 4–7 weeks after exposure to EBV(the virus which causes mono). The Monospot test proves positive in 90% of adults with the virus, but many children will display false negatives.hence in 10% of the cases sympptoms of the case can persist even after spot test is negative. for now i would advise you to- 1.avoid strenuous activities and athletic events until symptoms decrease which is normally around two months. 2.To relieve the sore throat, drink water, non-citrus fruit juices, and eat bland foods. 3. Acetaminophen or non-steroidal anti-inflammatory drugs along with high fluid intake wishing you good health, thanks