Hi, thanks for posting the concern in HCM. My understanding is, Ibuprofen or Tylenol is helpful in symptomatic relief from fever or throat pain. But, prolonged or frequent use may have serious side effects. Regarding your sore throat, I would say that is most commonly caused by viruses and the condition is self limiting. You can have steam inhalation twice daily and gurgle with lukewarm water for earlier recovery. If the condition worsens, you may need antibiotic treatment. Finally, if you take Ibuprofen, please have it post meal and have Tab Rantac or a PPI before meal to prevent gastric erosion. For any further information, please write back to me directly. Regards.