Hello Thanks for posting your query Prevention of progression of diabetic nephropathy first and for most intervention is Sugar contol round the clock Keep your HbA1C Avoid nephrotoxic agents like antibiotic amikacin gentamicin, pain killer voveran, dye used in radiological studies Water intake should be adequate if heart function is normal should not be too less Some medication delay progression of diabetic nephropathy like ACE inhibitor (Remipril-Cardace) Lastly be in regular follow up and get kidney function and electrolyte test regularly Hope this answers your query. If you have additional questions or follow up queries then please do not hesitate in writing to us. I will be happy to answer your queries. Dr Jeetendra Sharma Senior Consultant Critical care Medicine