Diabetic nephropathy

What is Diabetic nephropathy?

Diabetic nephropathy is a progressive kidney disease caused by angiopathy of capillaries in the kidney glomeruli. It is characterized by nephrotic syndrome and diffuse glomerulosclerosis. It is due to longstanding diabetes mellitus, and is a prime indication for dialysis in many Western countries. It is classified as a microvascular complication of diabetes.

Questions and answers on "Diabetic nephropathy"

Hello Doctor I am female of 43 years, since October 2012 I m getting high leak of protein in urine around 207 mg/L per day. My renal profile is normal. I have very slight diabetes and hypertension for which i m taking Zestril 10mg. Today my report for Vitamin D came deficient 20.69 nmol/L. Doctor please advice what is the reason for protein leak and Vitamin D. What precaution i have to take.

doctor1 MD

IN YOUR CASE -PROTEIN LEAK IN URINE IS STAGE 1 KIDNEY DISEASE IS DUE TO DIABETES ( CALLED DIABETIC NEPHROPATHY -Glomerular diseases are also accompanied by disruption and loss of the epithelial foot process covering of the basement membrane.

OTHER CAUSE MAY BE
High blood pressure
Infection
Reflux...

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Hi, i am a diabetic patient since 18 years, now the albumin is present in my urine sample since 1 year, but the blood urea and creatinine is normal and scanning report of kidney also normal, the doctor says here, i am admitted for test for kidney biopsy, please advise me sir. and also i have no retinopathy and any heart diseases.

doctor1 MD

Hi Chandru,.....albuminuria is an early sign of kidney disease...now it could be because of diabetes or any other cause also in your case....hence, consult a nephrologist, get quantification of your proteinuria and if necessary get a kidney biopsy done...if it turns out to be diabetic nephropathy...

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my mother is diabethic as she is suffering from diabetic nephropathy as her creatinine level is 2.4 and urea level is raised m.d. advises to get dialysis and ref nephroligist as she is 74 of age at present her infection level also high kindly advise what type of treat ment medicene can be taken

doctor1 MD

Hi,
Thanks for asking.
Based on your query, my opinion is as follows.
1. Good glucose control is necessary to prevent progression of diabetic neuropathy and well as all other complications, including nephropathy. Check HbA1C levels, it should be within 6.5 at all times.
2. Evening primrose oil...

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Hi, My father is 70 years old and has been suffering from diabetes for the past 25 years. Last Tuesday he suffered from hypoglycemia ,and at the hospital also suffered a heart failure , according to echo cardiogram reports. For the past few days he was was also suffering from fever, stomach flu . His heart condition is now much better and stable, but for future course of action, how do we keep his blood glucose levels normal.

doctor1 MD

Hello and thanks for the query.
I will advise you to consult his doctor to see whether he has any diabetic Nephropathy ?His kidney function tests and total protein in urine must be checked up since in long standing diabetics,chances of diabetic Nephropathy is high and the dose of anti diabetic...

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my father is suffering from kidney disorder .His critnine value is 5.9 .his debatis is 149 and bp is 170

doctor1 MD

Brief answer.
High creatinine with diabetes and high blood pressure indicates kidney damage called as diabetic nephropathy.

Detailed answer...

Hello,
Thanks for the query.
Diabetes is the leading cause for kidney problems, and high creatinine levels indicate kidney damage.
Ideally your father...

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can ACE/ARB be used at creatinine levels of 3.5 and potassium 4.8 for patient aged 75 with diabetes, HT and proteinuria+++ currently using stamlo 5 and moxovas 0.2(twice) will the switch be beneficial, it seems ACE/ARB are better for diabetic nephropathy .Also moxovas (contradicted for GFR 30) and stamlo (causing swelling and slowly progresses renal failure ) are they really suitable for stage 4 CKD

doctor1 MD

Hello,
You are absolutely right that MOXOVAS is avoided in patients having renal impairment.
Stamlo also should also be avoided.
ACE inhibitors and ARB's are definitely advised and they help in delaying the progression from diabetic nephropathy to ESRD ( end stage renal disease ).
Please don't...

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my mother is heart Patient is a known case of uncontrolled diabetes and diabetic nephropathy hence her urea and creatinine levels are above the reference range at the time of joining it was 109 on 27.01.10 then it came down to 55 on 16.02.10 and at present it is 83 on 02.03.10 hence Chelation is contra indicated at present because of her elevated renal profile. So the patient has been referred to specialist dialectologist and nephrologists for their expert opinion and management

doctor1 MD

Hi and welcome to HCM.
As an Urologist,i can understand your anxiety.You should write her age.
Your mother has Diabetic nephropathy,CKD and CAD.
In CKD treatment,she needs follow-up,with a nephrologist and tests like :
1. urine routine,culture and ACR.
2. blood...

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I am a diabetic patient from 10 years. Now I am having foot swelling . and my urine is also little foamy. My doctor orderd some urine tests and confirmed that i am having diabetic nephropathy. I am very scared now. pls help me. to come out of this is this dangerous ?

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hello doc. my father is a diabetic and a b.p patient. currently his serum creatnine is 2.1 , blood urea is 56 , potassium is 6.3 , na is 139 uric acid , total protein and albumin are in the normal range. he is under the following medication - b.p - losakar 50mg , sugar - zoryl m1 & glvus 50mg. Kindly suggest a proper indian veg. diet for him

doctor1 MD

Hello,
The reports of your father states that creatinine levels and potassium levels are high.
You should get these values repeated.If you still find them high,then it gives a strong suspicion of diabetic nephropathy and then you must consult a nephrologist for further treatment.
However a level...

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I am diabetic with low dosage of human mixtard insulin inj.(10 U-8U0,GLYNASE 1/2-1/2 and hypertensive with telsatran 40 and easm 5 daily .Taking ALFAD3=SHELCAL.SUGAR and BP under control.Creatinin was 1.6 for long with blood urea under 40 for long..recently creatinin increased to 2.0 and blood urea 55.uric acid crystals seen in urine and blood uric acid is 9.0..what medication should I take in addition to contol this quickly,,No swelling anywhere,no gout visually seen .

doctor1 MD

Hi user
Thanks for posting your query o Healthcare Magic
You are developing diabetic nephropathy which is a long term complication of diabetes.
To avoid kidney dysfunction following should be done.
1. Round the clock sugar control witn target HbA1c
2. Use of ACE inbitors or ARB drugs (you are...

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Recent questions on  Diabetic nephropathy

doctor1 MD

Dear sir, My husband is Type 1 diabetic for the past 15 years and nephorotic for the past 3 years, he is 36 years old now. He is supposed to take ACE inhibitors for the proteinuria. But his body is reactive to ACE inhibitors. So he is not taking any of the drug to stop the worsening of the kidney function. His cretinine value keeps fluctutuating between 1.0 and 2.6. But his ckp in elevated. cholestrol and BP is high. In this past 3years after becoming a nephrotis he had loads of probems. He had fistulla and that was removed. He had bone TB on the rib. Then a small bit of rib was removed. Now he was alright. Every month we have been checking his cretinine value, hemoglobin level and everything. Things are going well. But suddenly i observed a bulge on his right chest which looks like a fibroid, but not yet confirmed we haven t consulted the doctor which we will do in couple of days. So what can we do for this, will that dissolve by taking medicines or only through sugery. If that is possible through surgery can we go for laser? Without taking ACE inhibitors how long his kidney work or Is there any other medicines or any other way to stop worsening his kidney condition, Please suggest me............. Why his cpk is always high? We checked with the neurologist, we took relevant test, The doctor said that he does not have any neurological problems......Doctor says his decease does not follow the pattern of normal diabetic nephropathy because, his creatinine values goes suddenly up like 3 and with in two months setteled down to 1.2 like that...... Is it associated with any other decease....... kindly tell me? If you need any medical records of him I am ready to send kindly guide us please................

doctor1 MD

my mother in law is 65 years old and has slight watery blood in her urine. There is no pain anywhere at all. She is diabetic and has high blood pressure. We thought it was a urine infection and the doctor prescribed some antibitics however the blood is still there can you help?

doctor1 MD

My father is 70 years old and has been detected with out of bound reports for some of the Tests related to Kidney . Attached are prescriptions and reports. I need your guidance on how to proceed further. Here are some artifacts: 1. He underwent...

doctor1 MD

I have contacted you many times before. My name is Gopalakrishnan and my contact number is 0000. As per my recent medical report my creatinine serum level is 1.79 and blood urea level is 51.5 My HBA!C is 6.9 My blood presuure is very well under...

doctor1 MD

Sir,I am a teacher unable to move towards you.but trying to meet you shortly.Before that I would like to ask you that I am suffering from diabetics 2 type having 110 to 140 auger level and taking glicomet2 regularly since last three months.My...

doctor1 MD

my mother is heart Patient is a known case of uncontrolled diabetes and diabetic nephropathy hence her urea and creatinine levels are above the reference range at the time of joining it was 109 on 27.01.10 then it came down to 55 on 16.02.10 and at present it is 83 on 02.03.10 hence Chelation is contra indicated at present because of her elevated renal profile. So the patient has been referred to specialist dialectologist and nephrologists for their expert opinion and management

doctor1 MD

My mum had a diereya from last 4days. She did about 10 to 15 phooh a day, not eating and rely on drips in hospital. She had a blood test 2 days before she go to hospital and the report showing albuminuria.... Uti and intrinsic renal disease includ diabetic nephropathy. Her tummy size get big as we'll.

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