Side effects of Acitrom: Adverse ReactionsAs with all anticoagulants, bleeding is the major adverse effect of acenocoumarol. Hemorrhage may occur at virtually any site. Risk is dependent on multiple variables, including the intensity of anticoagulation and patient susceptibility. Cardiovascular: Hemorrhagic shock Central nervous system: Fever, headache, stroke (hemorrhagic) Dermatologic: Rash, urticaria, skin necrosis Skin necrosis/gangrene, due to paradoxical local thrombosis, is a known but rare risk of oral anticoagulant therapy. Its onset is usually within the first few days of therapy and is frequently localized to the limbs, breast, or penis. The risk of this effect is increased in patients with protein C or S deficiency. Additional adverse reactions associated with warfarin, but likely to also occur with indanediones, include priapism and skin necrosis (“purple toe” syndrome or cutaneous gangrene). Gastrointestinal: Gastrointestinal bleeding, melena Genitourinary: Hematuria Hematologic: Hemorrhage, retroperitoneal hematoma, unrecognized bleeding sites (eg, colon cancer) may be uncovered by anticoagulation. Other hematologic reactions reported with coumarin derivatives include agranulocytosis, red cell aplasia, anemia, thrombocytopenia, eosinophilia. Hepatic: Hepatitis, hepatotoxicity, hematobilia Ocular: Ocular hemorrhage Respiratory: Epistaxis, hemoptysis, pulmonary hemorrhage Miscellaneous: Hypersensitivity/allergic reactions . but in ur moms case its difficult to comment as the disease thats cancer stomach itself can cause bleeding . consult ur dr.