Hi priyanshu piyush Thanks for coming to HCM Your regimen is OK continue with it for a total course of 6 months.....your intensive phase i.e duration of taking AKT4 was prolonged for 1 month...it should have been for 2 months.... increased serum uric acid or hyperuricemia can be a side effect of pyrazinamide, a constituent of AKT4,,, but you are off that drug now, so no problem with AKT2. acute joint pain can be relieved by taking analgesics like ibuprofen, indomethacin etc... once off the symptoms recheck serum uric acid if it is raised the allopurinol can be started... for your swelling kindly go for renal function test i.e serum creatinine, urea and electrolytes....if abnormal meet your doctors....AKT can be continued even then also... best wishes