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Prescribed AKT 4 for TB detected from mantoux test. Swelling in face, eyes, legs and hands. Causes and cure ?

I am a 38 year old Lady. in october 2012 , tuberculosis was detected in my body after a positive montoux test and after that i was prescribed AKT4 FOR FIRST THREE months and after that AKT 2 was prescribed.. But from last 1 month my face specially eye and body parts like leg and hand have swelled up. also i am suffering from joint pain a report states that I have increased level of uric acid in my Body.... what are the cause and how can i get cured from this...? please help me soon...
Asked On : Mon, 8 Apr 2013
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Pulmonologist 's  Response
Hi priyanshu piyush
Thanks for coming to HCM
Your regimen is OK continue with it for a total course of 6 months.....your intensive phase i.e duration of taking AKT4 was prolonged for 1 should have been for 2 months....

increased serum uric acid or hyperuricemia can be a side effect of pyrazinamide, a constituent of AKT4,,, but you are off that drug now, so no problem with AKT2.

acute joint pain can be relieved by taking analgesics like ibuprofen, indomethacin etc... once off the symptoms recheck serum uric acid if it is raised the allopurinol can be started...

for your swelling kindly go for renal function test i.e serum creatinine, urea and electrolytes....if abnormal meet your doctors....AKT can be continued even then also...

best wishes

Answered: Mon, 8 Apr 2013
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