Brief Answer: You should be revaccinated at the appropriate time interval for each vaccine. you to take the antibiotic at the first sign of infection. Detailed Answer: Hello, Thank you for using HCM. As you are a splenectomised patient, you should have been vaccinated 14 days before or after the splenectomy depending on the circumstances of the operation, either it was planned or unexpected. In way to decrease the risk of overwhelming postsplenectomy infections, you should be revaccinated at the appropriate time interval for each vaccine. You should repeat the vaccine against Streptococcus pneumoniae (Pneumovax 23) every 6 years, and the vaccine against Neisseria meningitidis (ƒMenactra or Menomune-A/C/Y/W-135) every 3-5 years. Mean while the vaccine against Haemophilus influenzae type B (HibTITER) has no need to be repeated. Taking an antibiotic every daily basis can significantly reduce the risk of infection, but this is more recommended in children. As the adults, have a low risk of sepsis (severe and potentially life-threatening condition in which infection-causing bacteria spread throughout the bloodstream and/or tissues and impair normal body functions), the value of daily antibiotic treatment for adults is debated. I would suggest you to take the antibiotic at the first sign of infection, such as fever, chills, sore throat, or cough, and to see an infections diseases doctor immediately after that. Regarding the work, if you can find an alternative job with less contact with the patients, it would be better for your health. Hope this is helpful. Let me know if you need more clarifications. Otherwise please close and rate the answer. Kind Regards, Dr. Juarda