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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Had Convulsion. Prescribed Eptoine. Developed Fever, Low WBC Count. Reaction To Eptoine Or Viral Fever?

My wife recently had 1st convulsion at 46 years of age. It was severe one. Admitted to the hospital, Started Eptoine & within a weeks time she started getting fever for 5-6 days. We had to admit her to the hospital as WBC count went low to 2000. We strongly feel it could be a raection to Eptoine. However, doctors at the hospital keep saying it s some kind of viral fever. Pl. guide. Regards, C J Shah
Mon, 17 Dec 2012
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Psychiatrist,  's  Response
Hello,
Eptoin is a good drug for seizure and is time tested. Leokopenia ( a low WBC count) is one of the adverse reaction to Eptoin. It is not common but can occur. The best way is to stop the eptoin as of now and start some other drug as there are many new and safe drugs for epilepsy available in the market. A viral fever may lower the counts but when there is an obvious relation with the onset of the drug, one has to be come cautious. May be you can assert that you want the eptoin to be shifted to valproate or levetiracetam.
Hope I am able to solve your concerns. Hope your wife gets well soon.
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Had Convulsion. Prescribed Eptoine. Developed Fever, Low WBC Count. Reaction To Eptoine Or Viral Fever?

Hello, Eptoin is a good drug for seizure and is time tested. Leokopenia ( a low WBC count) is one of the adverse reaction to Eptoin. It is not common but can occur. The best way is to stop the eptoin as of now and start some other drug as there are many new and safe drugs for epilepsy available in the market. A viral fever may lower the counts but when there is an obvious relation with the onset of the drug, one has to be come cautious. May be you can assert that you want the eptoin to be shifted to valproate or levetiracetam. Hope I am able to solve your concerns. Hope your wife gets well soon.