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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Elevated Liver Enzymes, Abdominal Pain, Less Appetite. Taken Tablets For Heavy Periods. Reason?

Dear Doctor,
Yesterday I have done my Liver Function Test and observed that the SGOT and SGPT are increased to 653 and 1164 respectively. Besides my Bilirubin (Total) is 4.4. During last two months I have been taking Levonorgestrel and Ethinylestradiol tablets for my painful periods. I am suffering from abdominal pain with dark urine and less appetite. What are possible causes for this abnormal test result? What are the precautions?
Thu, 10 Oct 2013
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Gastroenterologist,  's  Response
Hello! Thanks for putting your query in HCM. I am a Gastroenterologist (DM).

This high elevation in transaminase levels in you may be due to:
1. Drug induced- levonorgestrol and ethinylestradiol
2. Acute viral hepatitis (Hepatitis A, B or E)

So I will advise you to stop these medicines and get test for acute viral hepatitis (IgM anti HAV, Igm anti HEV, HBsAg, and IgM anti HBc antibody)

And get repeat liver function tests may be after a week to see for the trend of these blood tests

I hope I have answered your query and this will help you. If you have any further query I will be happy to answer that too. Remain in touch and get-well soon.
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Elevated Liver Enzymes, Abdominal Pain, Less Appetite. Taken Tablets For Heavy Periods. Reason?

Hello! Thanks for putting your query in HCM. I am a Gastroenterologist (DM). This high elevation in transaminase levels in you may be due to: 1. Drug induced- levonorgestrol and ethinylestradiol 2. Acute viral hepatitis (Hepatitis A, B or E) So I will advise you to stop these medicines and get test for acute viral hepatitis (IgM anti HAV, Igm anti HEV, HBsAg, and IgM anti HBc antibody) And get repeat liver function tests may be after a week to see for the trend of these blood tests I hope I have answered your query and this will help you. If you have any further query I will be happy to answer that too. Remain in touch and get-well soon.