Question: My son was taking 250mg of Depakote for 2 weeks for his migraines (caused by brain seizures) and they became much worse. We stopped the medicine, went to the neurologist and they did blood work. When his blood test came back his depakote level was 4 and his topamax was 7. Is this normal? The neurologist will no longer treat him and I think it is because of the blood work.

I do not have the blood test report with me but I did look at it this morning and his Depakote blood level was 4.0 and his Topamax was 7.4. We stopped the Depakote because he went from having 2-3 migraine-type headaches a week to having one every day for 2 weeks. The only thing that changed was the addition of the Depakote. He was taking Gabapentin before we took him off (gradually) so that he could have an EEG without the interference of his medication. This is when they diagnosed that it was brain seizures (Epilepsy) causing his headaches. He is taking the Gabapentin again at this time because the medicine they wanted to give him had the potential for worse side effects. The neurologist was supposed to get back to us within the week to determine the next step but instead he dropped us as his patient and said there was nothing more he could do.