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What Causes Elevated Total Serum Protein?

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Posted on Mon, 10 Aug 2015
Question: I am concerned about an elevated protein total serum. Previously it was up to nine but has gradually come down to 8.3. My doctor wants me to have a protein electrophoresis blood test. What causes an elevated protein and is it necessary to have this test when the number has come down so much?
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Answered by Dr. Panagiotis Zografakis (52 minutes later)
Brief Answer:
dehydration usually

Detailed Answer:
Hello,

a high total serum protein is usually caused by dehydration. The interesting part about serum proteins is the measurement of albumin and globulins. If the globulins are elevated then this is a cause for concern. In that case, serum protein electrophoresis is warranted. Otherwise there is no need for it.

I hope I've addressed your concerns!
If you'd like any clarification or further information, please contact me again. I'll be glad to help!

Kind Regards!
Note: For further follow up on related General & Family Physician Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Panagiotis Zografakis

Internal Medicine Specialist

Practicing since :1999

Answered : 3809 Questions

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What Causes Elevated Total Serum Protein?

Brief Answer: dehydration usually Detailed Answer: Hello, a high total serum protein is usually caused by dehydration. The interesting part about serum proteins is the measurement of albumin and globulins. If the globulins are elevated then this is a cause for concern. In that case, serum protein electrophoresis is warranted. Otherwise there is no need for it. I hope I've addressed your concerns! If you'd like any clarification or further information, please contact me again. I'll be glad to help! Kind Regards!