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What causes blurred vision while suffering from vitamin B12 deficiency?

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Posted on Thu, 19 May 2016
Question: Hi, my eyesight has been getting blurry for the last 8 months almost to the point where I can't drive now. I had my eyes checked about 6 months ago and they said my eyes are normal for my age 42yrs. I have severe B12, Biotin and Folate. I am low in the whole B complex. It seems I can't get the B12 into the cell. When I take some B12 it bottoms out my folate and when I take folate it seems to bottom out my B12. Tests show I have lots of B12 in the blood but it doesn't seem to get into the cell well. I am very concerned with my eyesight and worried of losing it. I have all amino acid tests etc. done.
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Answered by Dr. Erion Spaho (1 hour later)
Brief Answer:
Eyesight impairment probably due to optic nerves damage.

Detailed Answer:
Hello and thanks for using HCM.

I have read your query and understand your concerns.

Blurry eyesight is probably related to optic nerves damage due to lack of vitamin B12.

Besides deficiencies of vitamin B12 related to low intake, malabsorption, gastrointestinal problems, lupus and Grave's diseases, genetic disorders of vitamin B12 metabolism are known as well.

These genetic disorders result in conditions such homocystnuria and methylmalonic aciduria implicating enzymes that utilize vitamin B12.

If these conditions are confirmed, treatment consists on high amounts of vitamin B12 intake, together with Folic acid intake.

I suggest you to discuss with your treating Doctor about getting tested to diagnose above mentioned conditions.

I didn't find any imbalance that could justify your concerns after the reports examination, uploaded by you.

Hope you found the answer helpful.

Let me know if I can assist you further.

Greetings.

Above answer was peer-reviewed by : Dr. Arnab Banerjee
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Follow up: Dr. Erion Spaho (14 minutes later)
We are struggling to find a doctor that understands about this. The reports attached have the test results with do show some genetic issues that may be implicating the enzymes that use B12. The B12 is getting into the blood but not the cells. Any suggestions or type of doctor that specialises in this type of thing would be great.
doctor
Answered by Dr. Erion Spaho (36 minutes later)
Brief Answer:
A team of Doctors needed.

Detailed Answer:
Welcome back.

Your condition is a rare one, in my opinion, you should be evaluated by a team of Doctors that includes a Neurologist, a Geneticist ( genetics Doctor ) and an Ophthalmologist.

If it was confirmed to you that actually is a enzyme that processes the vitamin B12 deficiency, improving your condition needs high doses of vitamin B12.

Hope I've been of help.

Wishing you good health.


Above answer was peer-reviewed by : Dr. Arnab Banerjee
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Answered by
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Dr. Erion Spaho

Neurologist, Surgical

Practicing since :2004

Answered : 4327 Questions

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What causes blurred vision while suffering from vitamin B12 deficiency?

Brief Answer: Eyesight impairment probably due to optic nerves damage. Detailed Answer: Hello and thanks for using HCM. I have read your query and understand your concerns. Blurry eyesight is probably related to optic nerves damage due to lack of vitamin B12. Besides deficiencies of vitamin B12 related to low intake, malabsorption, gastrointestinal problems, lupus and Grave's diseases, genetic disorders of vitamin B12 metabolism are known as well. These genetic disorders result in conditions such homocystnuria and methylmalonic aciduria implicating enzymes that utilize vitamin B12. If these conditions are confirmed, treatment consists on high amounts of vitamin B12 intake, together with Folic acid intake. I suggest you to discuss with your treating Doctor about getting tested to diagnose above mentioned conditions. I didn't find any imbalance that could justify your concerns after the reports examination, uploaded by you. Hope you found the answer helpful. Let me know if I can assist you further. Greetings.