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What Causes Bleeding Under Skin After Taking Depo-medrol Injection?

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Posted on Tue, 23 Sep 2014
Question: after taking injections of depo-medrol , 20mg/mi about every three weeks, it caused bleeding under skin resembling a blood blister usually along a vein . thin skin on hands and feet . removed a bandage on left hand , caused a quarter sized piece of epidermis to come off. feet are shedding skin but no bleeding. I have had chronic gout for the last 30 years.i did not have this problem previous to the injections . I take iv's of ketorolac 30 mg, hydromorphone 1 mg during the same period. I no longer take depo-medrol. any solurtions.

XXXXXXX XXXX

doctor
Answered by Dr. Arun (6 hours later)
Brief Answer:
Monoclonal antibodies are new treatment for Gout

Detailed Answer:
Hi XXXXXXX XXXX
wish you a best health at health care magic,
I am Dr. Arun Tank my specialization is Pathologist and Microbiologist hope I can able to answer your query.

I think you are suffering from Gout and to get relief from pain you are using a depo-medrol injection. I want to tell you that when you use steroids for long time you get some of the side effects. This side effect is epidermal atrophy as complained by you as a skin shedding but no bleeding. This effect will not appear when you use it for short time but as you are a patient of Gout you have to use it frequently that I understand.

There are some other kind of treatment newly available in the market "Monoclonal Antibodies" which is very helpful to the persons who is having side effects with the steroids you can discuss that with your treating Doctor. By using this you will have to use low dose of steroids.

For the purpose of maintenance there are some other drugs available that you can discuss with your treating doctor like Colchicine, Allopurinol, Diuretics.

There are other non pharmacological measures which I want to advice you
* Reduction in weight
* Decrease intake of food rich in purines like meat, fish crab etc.
* Avoid alcohol intake
* Keep affected area in cool atmosphere
* Avoid dehydration
* Avoid trauma to affected part
* Maintain optimal uric acid level in the blood.

I hope I answered your query. If you have anything else to ask kindly contact me. If you are satisfied with the answer kindly close the question and rate my answer.
Thank you for your contact to healthcare, we wish you a best health.

Note: Do you have more questions on diagnosis or treatment of blood disorders? Ask An Expert/ Specialist Now

Above answer was peer-reviewed by : Dr. Vaishalee Punj
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Answered by
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Dr. Arun

Infectious Diseases Specialist

Practicing since :2008

Answered : 2434 Questions

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What Causes Bleeding Under Skin After Taking Depo-medrol Injection?

Brief Answer: Monoclonal antibodies are new treatment for Gout Detailed Answer: Hi XXXXXXX XXXX wish you a best health at health care magic, I am Dr. Arun Tank my specialization is Pathologist and Microbiologist hope I can able to answer your query. I think you are suffering from Gout and to get relief from pain you are using a depo-medrol injection. I want to tell you that when you use steroids for long time you get some of the side effects. This side effect is epidermal atrophy as complained by you as a skin shedding but no bleeding. This effect will not appear when you use it for short time but as you are a patient of Gout you have to use it frequently that I understand. There are some other kind of treatment newly available in the market "Monoclonal Antibodies" which is very helpful to the persons who is having side effects with the steroids you can discuss that with your treating Doctor. By using this you will have to use low dose of steroids. For the purpose of maintenance there are some other drugs available that you can discuss with your treating doctor like Colchicine, Allopurinol, Diuretics. There are other non pharmacological measures which I want to advice you * Reduction in weight * Decrease intake of food rich in purines like meat, fish crab etc. * Avoid alcohol intake * Keep affected area in cool atmosphere * Avoid dehydration * Avoid trauma to affected part * Maintain optimal uric acid level in the blood. I hope I answered your query. If you have anything else to ask kindly contact me. If you are satisfied with the answer kindly close the question and rate my answer. Thank you for your contact to healthcare, we wish you a best health.