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Question: I have been diagnosed with psoriasis. No family history of this disorder. I have noticed that most of the eruptions occur in high body heat areas (and low sun light exposure) such as, under arm, groin, and buttocks (from sitting). Is this a standard symptom? If so, are there ways to better control these areas?
XXXXXXX .
Brief Answer:
Flexural Psoriasis
Detailed Answer:
Hello and welcome to healthcaremagic
I am Dr. Kakkar. I have gone through your query and I have understood it.
Psoriasis typically affects extensors like scalp, elbow, knee, lower back, shins etc. However there is a type of psoriasis called "Sebopsoriasis or Inverse Psoriasis" which is characterised by involvement of the flexors like groins, axilla and butt folds rather than the extensors. This type of involvement is well known in psoriasis.
It is common for patients to have both kinds of involvement, extensor as well as flexural.
Just like psoriasis involving extensors, flexural psoriasis is also very responsive to topical steroids as well as topical tacrolimus (an immunomodulator). I usually avoid steroids in flexural areas because of the risk of atrophy and I prefer tacrolimus in my patients with flexural involvement
Tacrolimus is a prescription drug and therefore I would suggest that you seek an appointment with a dermatologist and inquire about it.
Regards
Flexural Psoriasis
Detailed Answer:
Hello and welcome to healthcaremagic
I am Dr. Kakkar. I have gone through your query and I have understood it.
Psoriasis typically affects extensors like scalp, elbow, knee, lower back, shins etc. However there is a type of psoriasis called "Sebopsoriasis or Inverse Psoriasis" which is characterised by involvement of the flexors like groins, axilla and butt folds rather than the extensors. This type of involvement is well known in psoriasis.
It is common for patients to have both kinds of involvement, extensor as well as flexural.
Just like psoriasis involving extensors, flexural psoriasis is also very responsive to topical steroids as well as topical tacrolimus (an immunomodulator). I usually avoid steroids in flexural areas because of the risk of atrophy and I prefer tacrolimus in my patients with flexural involvement
Tacrolimus is a prescription drug and therefore I would suggest that you seek an appointment with a dermatologist and inquire about it.
Regards
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
If I understand psoriasis, it is the autoimmune system trying to defend against an infection that is not there. So for some reason, I am affected in body areas that I would normally develop a heat rash.
Perhaps I am inquiring about medicine we have no answer, but it would seem to me that my outbreak is focused on the previously described areas and not, for example, outbreaking on my left ear or bottom of my feet.
Is there any medical references to new research on reasons for psoriasis?
Topical creams only make the eruptions fade faster, not prevent them. XXXXXXX ..
Perhaps I am inquiring about medicine we have no answer, but it would seem to me that my outbreak is focused on the previously described areas and not, for example, outbreaking on my left ear or bottom of my feet.
Is there any medical references to new research on reasons for psoriasis?
Topical creams only make the eruptions fade faster, not prevent them. XXXXXXX ..
Brief Answer:
Psoriasis
Detailed Answer:
Hi.
Psoriasis is an immune mediated disease primarily driven by dysregulated immune system (primarily T cell driven disease) and the cytokines(mainly TNF-alpha) secreted by immune cells primarily T-cells. There are a lot of Biologic therapeutic agents like adalimumab, infliximab etc that have become available in the last few years that specifically target TNF-alpha and effectively control psoriasis(particularly widespread psoriasis) with long term remissions thus improving the quality of life. The disease is bound to relapse, nevertheless but the remissions are longer with newer therapies like Biologics. However for localized disease, topical therapies are still preferable.
You can go through the following links for an insight:
http://www.ncbi.nlm.nih.gov/pubmed/0000
http://www.ncbi.nlm.nih.gov/pubmed/0000
http://www.ncbi.nlm.nih.gov/pubmed/0000
Regards
Psoriasis
Detailed Answer:
Hi.
Psoriasis is an immune mediated disease primarily driven by dysregulated immune system (primarily T cell driven disease) and the cytokines(mainly TNF-alpha) secreted by immune cells primarily T-cells. There are a lot of Biologic therapeutic agents like adalimumab, infliximab etc that have become available in the last few years that specifically target TNF-alpha and effectively control psoriasis(particularly widespread psoriasis) with long term remissions thus improving the quality of life. The disease is bound to relapse, nevertheless but the remissions are longer with newer therapies like Biologics. However for localized disease, topical therapies are still preferable.
You can go through the following links for an insight:
http://www.ncbi.nlm.nih.gov/pubmed/0000
http://www.ncbi.nlm.nih.gov/pubmed/0000
http://www.ncbi.nlm.nih.gov/pubmed/0000
Regards
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Thank you. I read those and it seems for such a common disease, we know more about the common cold or the ebola virus than psoriasis.
I am thinking out loud about why the sudden change for me after 60 years. I have not had a virus for 3 years. It is the first time that can remember not getting a common cold at least once in a year. Joking...Is my immune system angry with me being healthy?
Can a Dermatologist diagnose psoriasis visually only? Would a blood test show excess T-cells? XXXXXXX ..
I am thinking out loud about why the sudden change for me after 60 years. I have not had a virus for 3 years. It is the first time that can remember not getting a common cold at least once in a year. Joking...Is my immune system angry with me being healthy?
Can a Dermatologist diagnose psoriasis visually only? Would a blood test show excess T-cells? XXXXXXX ..
Brief Answer:
Psoriasis
Detailed Answer:
Hi.
I apologize for the delay in my reply.
I can understand you dilemma about the whole situation.
Yes, Psoriasis is is commonly diagnosed visually. It is fairly classic in its presentation.
No blood tests won't show excess T- cells. Rather, it is the dysregulation of Immune cells (T- cells) that underlies psoriasis.
Regards
Psoriasis
Detailed Answer:
Hi.
I apologize for the delay in my reply.
I can understand you dilemma about the whole situation.
Yes, Psoriasis is is commonly diagnosed visually. It is fairly classic in its presentation.
No blood tests won't show excess T- cells. Rather, it is the dysregulation of Immune cells (T- cells) that underlies psoriasis.
Regards
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
What are the "non visual" tests to confirm psoriasis? XXXXXXX ..
Brief Answer:
Psoriasis
Detailed Answer:
Hi.
"Skin Biopsy for histopathologic examination" is confirmatory of psoriasis.
Regards
Psoriasis
Detailed Answer:
Hi.
"Skin Biopsy for histopathologic examination" is confirmatory of psoriasis.
Regards
Note: Hope the answers resolves your concerns, however for further guidance of skin related queries consult our Dermatologist.Click here to book a consultation
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
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