Have Enlarged Lymph Nodes In Neck, Weight Loss, Night Sweats. Family History Of Lymphoma And Leukemia. Worried
I am Dr. Prasad Akole (Critical Care Expert- http://bit.ly/Dr-Prasad-Akole) and am glad to address to your query here.
Significant weight loss, night sweats, lymph node enlargement in the neck I the absence of a recent infection in the upper body areas and a strong family history of lymphoma strongly point to a possibility of a lymphoma in the nodes.
Commonest cause of nodal enlargement is of course infections and a course of antibiotics for 7-10 days is warranted before conclusion about reactive nodes.
Leukemia/ lymphoma, other cancers, granulomatous diseases like tuberculosis and others are good differentials in such a case.
You have undergone a FNA (fine needle aspiration) which may miss a representative area affected by these diseases and only shows reactive picture if from adjacent areas.
A surgical lymph node biopsy is needed from biopsiable nodes in the neck (usually under local anaesthesia) and expert pathological impression about lymphoma is obtained.
A further search for any other sites of enlarged nodes must be sought (groins, armpits, in the abdomen and chest). It requires sonography and a CT sacn of the thorax and abdomen/pelvis.
Complete blood lab (routine), ESR, liver function tests are essential.
Absence of thyroid in the neck (what test was done?) with normal thyroid hormone level indicates the possibility of an ectopic thyroid. You may ask the endocrinologist about this possibility of a thyroid tissue at abnormal locations within your body (which secretes the hormones).
I hope to have answered your query satisfactorily. I would be glad to answer any further queries.
Take care and please keep me informed of your progress at http://bit.ly/Dr-Prasad-Akole
Good Luck!