Get your health question answered instantly from our pool of 18000+ doctors from over 80 specialties

198 Doctors Online
Doctor Image
Dr. Andrew Rynne

Family Physician

Exp 50 years

I will be looking into your question and guiding you through the process. Please write your question below.

Have elevated hpv antibodies, blood protein level, SED rate with inflammatory spondyloarthritis. Concerned?

Answered by
Dr. Divya Agarwal


Practicing since :1999

Answered : 581 Questions

Posted on Fri, 1 Feb 2013 in Lupus
Question: Hey,
I have a great rheumatologist at UCLA, and should probably relax, but..... He recently referred me to an Infectious Disease doctor, because I have elevated hpv antibodies, a blood protein level of 8.4, and a SED rate of 29. I have inflammatory spondyloarthritis, and have been receiving Remicade infusions for the past year. He said that he is concerned that I may have an underlying infection, but is not sure. Do you think I need to worry?
Answered by Dr. Divya Agarwal 2 hours later

You have elevated HPV antibodies, which suggest that you have had a papilloma virus infection in the past, but the question is that do you have any symptoms like warts or of active disease now?

The other thing is to actually diagnose the presence of high risk HPV virus, the kind associated with cervical cancer. You may need a pap smear and a HPV test, which is a DNA test (which is based on examination of cervical cells). Therefore, it may be a good idea to visit an Infectious Diseases specialist who can review these things.

Remicade as you know does suppress our immune system. However, on the basis of the test you described there should not be anything to worry and may require further testing at the discretion of the specialist.

Do write back if you wish to discuss further on this.

Above answer was peer-reviewed by : Dr. Shanthi.E
Follow up: Dr. Divya Agarwal 14 hours later
I had hpv in 1990, and had to have it removed, with laser surgery. I worry about the blood protein level though, as I know a high blood protein level can often be a sign of multiple myeloma or other lymphoma type cancers. A side effect of Remicade can sometimes be lymphoma. I have been taking tnf blocker medications for 3 years. I have to take these drugs, otherwise my inflammatory arthritis wreaks major havoc on my joints. It is destroying my shoulders, wrists and knees. The tnf blockers really help slow it's progress. My SED rate was 60 last fall. And we can't seem to get it below 29. Should I worry about lymhpoma? Or do you think it's just the hpv causing problems? I am going to see an Infectious Disease Dr. at UCLA later this month. I'm just trying to put my mind at ease.
Answered by Dr. Divya Agarwal 9 hours later
A lymphoma should be producing other effects apart from the high protein levels.

So I don't think this HPV titer is related to that.

Remicade is definitely giving you all the benefits in order to keep your arthritis under control.

It doesn't seem like a major problem.
I don't think you need to be worried on that account.

A high ESR, sometimes continues in spondyloarthritis and there is no correlation with the disease activity.

Above answer was peer-reviewed by : Dr. Shanthi.E

The User accepted the expert's answer

Share on
Question is related to
Diseases and Conditions ,   ,   ,   ,   ,   ,   ,  
Drug/Medication ,   ,  
Medical Procedures
Medical Topics ,   ,  

Recent questions on  Papillomavirus

doctor1 MD

I have no were else to turn for help. i have been suffering from warts for many years. i have 4 large pink warts on my index finger. plus many more around my finger nails. This issue has kept me from geting a job. what is the best proven treatment and the cost? Please help im desperate for answers thinks.

doctor1 MD

Well I have developed these bumbs on the outer side of my vagina. They are not genital warts because I am a virgin. They aren t gross looking either. They are red and some look like pimples. They are on my butt too a little bit. They are itchy and when i itch them they hurt. My dads girlfriend said it could be from shaving and a mixture of wearing pads. So for the last two days I have been wearing tampons but the bumps are still there and still itchy. I read some things and girls said pads are causing them to have like chemical burn, but these loads haven t ever bothered me this much. So I don t know what it is or what to do. What do you think?

doctor1 MD

i had a pap smear done and no scar tissue, i had a complete hysterectomy in 2004 i spot blood time to time, and i have lots of heart burns help need answers. im 44 years old. could i have acid reflux, i have a lump in neck, it is a lymph node, non cancerous, but gets flat, then comes back, very visual, help

doctor1 MD

Hello. I had a leep procedure done without my doctor doing a colpo. She mentioned that she will do the colpo during the leep procedure and that I need to have it done anyway because I came back at high grade HPV. She cut off a huge chunk of my cervix in which all of it was normal tissue. Now I m having all kinds of sharp pains in my pelvix, pain during intercourse and weird periods that stay on for about two weeks. I went to another obgyn who stated that this doctor should not have done the leep without doing the colpo first to see if it was even necessary. Do I have a lawsuit and what can I do about this?

doctor1 MD

I recently had a pap smear that came back ASC H. I had a colposcopy last week with the following results: Part A: CERVIX , 5:00, BIOPSY: LOW-GRADE SQUAMOUS INTRAEPITHELIAL LESION (CIN 1). KOILOCYTOSIS CONSISTENT WITH HUMAN PAPILLOMAVIRUS (HPV)...

doctor1 MD

Hi, I am 23yr old... I had unprotected sex with a guy when i am young before reaching my puberty(before commence of my 1st menstrual cycle) Is there chances of i getting pregnant...? I am scared of this and feel shy to consult a doctor and speak...

doctor1 MD

I have some very small pink round dots/marks around pubic area. they are hardly noticeable but they sometimes itch or are slightly painful. can you please let me know what this could be? (see attached photo). thank you