Get your health question answered instantly from our pool of 18000+ doctors from over 80 specialties

190 Doctors Online
Doctor Image
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

I will be looking into your question and guiding you through the process. Please write your question below.

Have elevated hpv antibodies, blood protein level, SED rate with inflammatory spondyloarthritis. Concerned?

Answered by
Dr.
Dr. Divya Agarwal

Rheumatologist

Practicing since :1999

Answered : 567 Questions

default
Posted on Fri, 1 Feb 2013 in Lupus
Question: Hey,
I have a great rheumatologist at UCLA, and should probably relax, but..... He recently referred me to an Infectious Disease doctor, because I have elevated hpv antibodies, a blood protein level of 8.4, and a SED rate of 29. I have inflammatory spondyloarthritis, and have been receiving Remicade infusions for the past year. He said that he is concerned that I may have an underlying infection, but is not sure. Do you think I need to worry?
doctor
Answered by Dr. Divya Agarwal 2 hours later
Hi,

You have elevated HPV antibodies, which suggest that you have had a papilloma virus infection in the past, but the question is that do you have any symptoms like warts or of active disease now?

The other thing is to actually diagnose the presence of high risk HPV virus, the kind associated with cervical cancer. You may need a pap smear and a HPV test, which is a DNA test (which is based on examination of cervical cells). Therefore, it may be a good idea to visit an Infectious Diseases specialist who can review these things.

Remicade as you know does suppress our immune system. However, on the basis of the test you described there should not be anything to worry and may require further testing at the discretion of the specialist.

Do write back if you wish to discuss further on this.

Above answer was peer-reviewed by : Dr. Shanthi.E
doctor
default
Follow up: Dr. Divya Agarwal 14 hours later
I had hpv in 1990, and had to have it removed, with laser surgery. I worry about the blood protein level though, as I know a high blood protein level can often be a sign of multiple myeloma or other lymphoma type cancers. A side effect of Remicade can sometimes be lymphoma. I have been taking tnf blocker medications for 3 years. I have to take these drugs, otherwise my inflammatory arthritis wreaks major havoc on my joints. It is destroying my shoulders, wrists and knees. The tnf blockers really help slow it's progress. My SED rate was 60 last fall. And we can't seem to get it below 29. Should I worry about lymhpoma? Or do you think it's just the hpv causing problems? I am going to see an Infectious Disease Dr. at UCLA later this month. I'm just trying to put my mind at ease.
doctor
Answered by Dr. Divya Agarwal 9 hours later
A lymphoma should be producing other effects apart from the high protein levels.

So I don't think this HPV titer is related to that.

Remicade is definitely giving you all the benefits in order to keep your arthritis under control.

It doesn't seem like a major problem.
I don't think you need to be worried on that account.

A high ESR, sometimes continues in spondyloarthritis and there is no correlation with the disease activity.

Above answer was peer-reviewed by : Dr. Shanthi.E
doctor
premium_optimized

The User accepted the expert's answer

Share on
Question is related to
Diseases and Conditions ,   ,   ,   ,   ,   ,   ,  
Drug/Medication ,   ,  
Medical Procedures
Medical Topics ,   ,  

Recent questions on  Papillomavirus

doctor1 MD

Bladder issues: leaking pee and a burning sensation during peeing. Dear reader, I am a 17 year old girl experiencing some bladder issues lately. My problems started about 1 1/2 month ago: I noticed I had to go to the toilet a lot, and I also noticed a burning sensation during peeing. I had to change panties quite often as I would find that they got really wet (not because i was aroused, I think it was sticky discharge combined with pee, because it was yellow colored). Also, when I have sex, I constantly have the feeling i have to pee (but that might also be because of the position). Around the time these symptoms occurred I also felt a slightly painful and uncomfortable feeling during sex. I thought I had a bladder infection, but when I tested for that the results came back negative. THen I went to the doctor, who couldn t think of anything else besides a possible yeast infection or STD. I got tested for both, but yet again the results came back negative. The symptoms went away for about a month, however the past few days I noticed that I ve started leaking again. It has come to the point where I have to change panties at least 3 times a day. I noticed that the fluid is very clear and that it is pee. I also feel a burning sensation during peeing and sometimes even when I am just sitting I can just feel some pee leaking out of me. Some extra useful information: -I have been sexually active for some less than 2 years now, have had the same partner all along, never contracted an STD. -Me and my boyfriend have sex without a condom, however I am using birth control pills (have been using then since the start of me becoming sexually active, so almost 2 years now) -Have had a yeast infection a few months ago, had it treated by putting a ball of cream (forgot the name of the thing) inside my vagina for three nights. -I have had a lot of problems with bleeding during intercourse. It started around the 5th time I had sex, and lasted for about 1.5 years. (However, there was a period during the summer of 2011 that I didn t bleed for 2 or 3 months). For the past few months I have not bled, which might have been a result of me changing my birth control pills. -The doctor performed a pap smear on me in April 2011, because of the problems I had with bleeding during sex. the result: I have pap-2 and do have the HPV virus. I am scheduled to undergo another pap smear in November, to see if it has gotten worse or better. -I do perform kegel exercises on a regular basis, and have been doing so even before I started to become sexually active. I do not think that my muscles are the problem. -I did a pregnancy test last month. The result was that I am not pregnant. Thank you for taking the time to try and help me with my problems, I really appreciate it. Also, I would like to note that I live in the Netherlands and English is not my mother tongue. I apologize for any mistakes or unclear explanations, I have tied to state everything as clearly as I could, however I found it a bit difficult. best regards, Roxanne

doctor1 MD

I have been seeing a girl 9 months....early on, I would develop a moist, foul smelling rash where I did t remove all of her Vaginal secretions weren't immediately removed....now I have a one inch line of raised, tough skin where the rash usually occurred.....freaking myself out reading about genital warts

doctor1 MD

Hi, i recently got married in the month of april, i have started getting cracks on the upper part of the skin covering the red head of my penis, there also is some extra skin growth type (may be warts) on the lower side of the penis head which has increased from 1 to 3, now i can see one on my wife's private part too, please advise. Age-35, Height-175cm, Weight-81, Family History has Sugar in family (Diabetes), please advice as m too worried.

doctor1 MD

hi, im 22 years old male, 5'6'', 165 lbs. My medical history is good. i dont have any health problems. im not allergic to anything i know of. i do smoke about 10 ciggerettes a day. i recently found a small cluster smaller than a dime in diameter of coliflower like bumps on my genitals just under my shaft on the sac connecting to the shaft of my penis. my concern is that i have genital warts or a type of hpv. is this a serious problem i have at hand? will these bumps go away? is there a medication to prevent bumps like this in the future? my partner has no idea of my situation and im afraid of rejection by her. is this a normal feeling if i do have a serious issue? how will this affect my sex life? please help im very concerned and thank you.

doctor1 MD

I recently had a pap smear that came back ASC H. I had a colposcopy last week with the following results: Part A: CERVIX , 5:00, BIOPSY: LOW-GRADE SQUAMOUS INTRAEPITHELIAL LESION (CIN 1). KOILOCYTOSIS CONSISTENT WITH HUMAN PAPILLOMAVIRUS (HPV)...

doctor1 MD

Hi, I am 23yr old... I had unprotected sex with a guy when i am young before reaching my puberty(before commence of my 1st menstrual cycle) Is there chances of i getting pregnant...? I am scared of this and feel shy to consult a doctor and speak...

doctor1 MD

I have some very small pink round dots/marks around pubic area. they are hardly noticeable but they sometimes itch or are slightly painful. can you please let me know what this could be? (see attached photo). thank you