Multiple myeloma

What is Multiple myeloma?

An uncommon disease that occurs more frequently in men than in women and is associated with anemia, hemorrhage, recurrent infections, and weakness. Ordinarily, it is regarded as a malignant neoplasm that originates in bone marrow and involves chiefly the skeleton, with clinical features attributable to the sites of involvement and to abnormalities in formation of plasma protein; characterized by numerous diffuse foci or nodular accumulations of abnormal or malignant plasma cells in the marrow of various bones (especially the skull), causing palpable swellings of the bones, and occasionally in extraskeletal sites; radiologically, the bone lesions have a characteristic punched-out appearance. The myeloma cells produce abnormal proteins in the serum and urine; those formed in any one example of multiple myeloma are different from other myeloma proteins, as well as from normal serum proteins, the most frequent abnormalities in the metabolism of protein being: 1) the occurrence of Bence Jones proteinuria, 2) a great increase in monoclonal γ-globulin in the plasma, 3) the occasional formation of cryoglobulin, and 4) a form of primary amyloidosis. The Bence Jones protein is not a derivative of abnormal serum protein, but seems to be formed de novo from amino acid precursors.

Questions and answers on "Multiple myeloma"

My mother who is 76 has multiple myeloma. She has had a recurrent problem with inflammation of the tear duct in her eye. She had surgery and was...

doctor1 MD

Hi, dear
I have gone through your question. I can understand your concern.
This problem is common. It is due to inflammation in lacrimal glabd or...

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Recent questions on  Multiple myeloma

doctor1 MD

My son is 34. Has multiple myeloma and has had so many problems from his ommya res. that they had to take it out. The brain bleeding could be from...

doctor1 MD

My father has multiple myeloma. he s on his third month of the BiRD treatment right now with Revlmid, biaxin and dexamethazone. his BP has been low...

doctor1 MD

I have had a severe bout of itching, hives, bruising that started about three days after my last dose of Nitrofurantoin on a ten day regimen,...

doctor1 MD

Hello I am 62 and I saw blood in my urine...subsequently had a urine cytology tested negative for cancerous cells and bacteria...had a transvaginal...

doctor1 MD

I have been nauseous for about a month, a few times I had pale stools now they are very loose, some loss of appetite, and fatigue . I had my...

doctor1 MD

My husband is 78 and has COPD , congestive heart failure , vascular dementia , multiple myeloma and Afib. He also suffers from chronic back pain...

doctor1 MD

I have dry eyes. I am going to a Opthamologist to check my sight because I believe it is diminishing. I have had dry eyes for the past 8 months....

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