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Does Warfarin Have A Negative Effect On Liver?

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Posted on Mon, 29 Sep 2014
Question: I have been prescribe coumadin therapy 3 mg. /day for past 9 years related to a
an atrial fib experience about 12 hrs. after a knee replacement in 2005?? Was back in
sinus rythmn within a short time in hospital;however, given a life sentence on warfarin. Have
consulted cardiologists in this home city but they all tell me it is to prevent me from having a CVA??
Thankfully, I have remained in 'sinus rythmn ever since (sp.) throughout except for palpatations/
especially when I was tired or stressed but other than that, I exercise,walk,etc. and thankfully stay
in sinus rythmn.
Since a recent abdominal scan, my liver is not happy....some abrasions, and right lobe enlarged??
thank you for consultation.
doctor
Answered by Dr. Jyothi B L (1 hour later)
Brief Answer:
Not advisable. However you can start another.

Detailed Answer:
Hi,
Thanks for asking.
I am Dr. Jyothi BL and I will be answering your query.

Looking at the medical history and current query, my opinion is as follows:

1. Warfarin is not responsible for your present liver scan findings. It rarely affects liver.

2. Discontinuing warfarin can caused rebound risk of thrombosis. You need to start on other anti-coagulants, if you want to discontinue this.

3. At this age, taking warfarin is advisable and reduces risk of not only CVA, but also myocardial infarction or any thrombosis, anywhere in the body.

Liver abrasions will heal. Right lobe enlargement alone will not be due to warfarin.

If you wish to discontinue warfarin, and go for another anticoagulant, then it takes time to adjust dose, monitor adverse reactions and keep watching out for side effects.

Hope it helps.
Any further queries, happy to help again.

Dr. Jyothi BL
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Yogesh D
doctor
Answered by
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Dr. Jyothi B L

Pathologist and Microbiologist

Practicing since :2003

Answered : 849 Questions

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Does Warfarin Have A Negative Effect On Liver?

Brief Answer: Not advisable. However you can start another. Detailed Answer: Hi, Thanks for asking. I am Dr. Jyothi BL and I will be answering your query. Looking at the medical history and current query, my opinion is as follows: 1. Warfarin is not responsible for your present liver scan findings. It rarely affects liver. 2. Discontinuing warfarin can caused rebound risk of thrombosis. You need to start on other anti-coagulants, if you want to discontinue this. 3. At this age, taking warfarin is advisable and reduces risk of not only CVA, but also myocardial infarction or any thrombosis, anywhere in the body. Liver abrasions will heal. Right lobe enlargement alone will not be due to warfarin. If you wish to discontinue warfarin, and go for another anticoagulant, then it takes time to adjust dose, monitor adverse reactions and keep watching out for side effects. Hope it helps. Any further queries, happy to help again. Dr. Jyothi BL