Get your Health question answered in 3 easy steps
A Doctor will be with you shortly
Ask a Doctor Now
170 Doctors are Online

Can endometriosis dry up on its own after stopping premarin?

User rating for this question
Very Good
Answered by
Practicing since : 2001
Answered : 12753 Questions
Can endometriosis dry up on its own after stopping Premarin? I'm taking progesterone which my gyno said will help dry it up. Also, I started taking Premarin immediately after my hysterectomy in 2000. I had to wean myself off because my gyno said it was feeding the endo. I've been off of Premarin for about 6 weeks now and feeling like I'm in full blown menopause. Is this possible?
Posted Tue, 7 May 2013 in Medicines and Side Effects
Answered by Dr. Rakhi Tayal 2 hours later
Thanks for posting your query.
Premarin contains conjugated estrogens which helps in the growth of ectopic endometrial tissue thus increasing the symptoms of endometriosis.
Progesterone suppresses the growth of endometrial tissue and a high dose therapy is recommended to get rid of the symptoms. Once the pain subsides, the progesterone therapy can be weaned off.
After hysterectomy, since you are symptom free, you can start gradual tapering off of progesterone or reduce the doses after consulting your gynecologist.
Hope this answers your query. I will be glad to answer the follow up queries that you have.
Please accept my answer in case you do not have further queries.
Wishing you good health.
Dr. Rakhi Tayal.
Above answer was peer-reviewed by
Follow-up: Can endometriosis dry up on its own after stopping premarin? 17 hours later
Thank you! How much progesterone do you recommend I be taking to get rid of the endometriosis? Also, it seems like I'm going through menopause or my hormones are just out of whack after stopping the Premarin. My endo symptoms I've noticed get worse certain times during a month. How long should it take for the progesterone to dry up the endo? And if the endo has spread to other areas, will the progesterone take care of it too? I'm wishing now that I would've had a laparoscopy done.
Answered by Dr. Rakhi Tayal 6 hours later
Thanks for writing again.
Initially high doses 200-400mg daily is needed according to the severity of the problem. After 2-3 months the doses are reduced or are given in the last 10 days of the cycle.
This high dose progesterone will take care of endometriosis at all the places.
Hope my answer is helpful.
Do accept my answer in case there are no further queries.
Above answer was peer-reviewed by
Share on Facebook
Share on Twitter
Share on Google+
Question is related to
Diseases and Conditions
Medical Topics

The user accepted the expert's answer

Ask an Internal Med Specialist

© Ebix, Inc. All Rights Reserved.
All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice. You should always speak with your doctor before you follow anything that you read on this website. Any health question asked on this site will be visible to the people who browse this site. Hence, the user assumes the responsibility not to divulge any personally identifiable information in the question. Use of this site is subject to our Terms & Conditions
Already Rated.
Your rating:

Ask a Doctor