Given your set of circumstances, yes---in a heartbeat (no pun intended). By definition, if you had angioplasty, things *aren t* normal. You have narrowed, diseased blood vessels.Your #1 aim is to minimize the risk of disease progression. Getting your cholesterol down is critical to this. It may not be a lifetime prescription---you may find that lifestyle changes make it unnecessary at some point. However, with your family history, it might well be something you do require for the long run. Lipitor is not risk-free---but you are in a very, very high-risk category, in terms of your cardiac status---so the risk vs. benefit ratio of the drug leans very heavily toward taking it. Stay healthy!