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Dr. Andrew Rynne

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Exp 50 years

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Will tabs folvite, sustain,dufaston ,injection chorionic humen gonadotrophin help to avoid miscarriage for a person with miscarriage history ?

dear sir there is a problem with my wife. she got pregnant now.but she become miscarriage(the foitus be dead after three month) 4 time,the doctor advise some tests like torch hemoglobin tsh .all test r normal but tsh in tsh the hormone become arise as6.9. now she is 83 days pregnancy . im afraid not to repeat last 4 times case. the priscripson is tab folvite 1 od,sustain tab 1 od,tab dufaston 1 tds,inj chorionic humen gonadotrophin at 7 days.please suggest me.thanks dear sir there is a problam with my wife. she got pregnanat now.but she become miscarrige(the foitus be dead after three month) 4 time,the doctor advise some tests like torch hemoglobin tsh.all test r normal but tsh in tsh the hormone become arise as6.9. now she is 83 days pregnancy. im afraid not to repeat last 4 times case. the priscripson is tab folvite 1 od,sustain tab 1 od,tab dufaston 1 tds,inj chorionic humen gonadotrophin at 7 days.please suggest me.thanks
Sun, 22 Jan 2012
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Pediatrician 's  Response
hello rohit,
most common causes of 1st trimester abortion are genetic cause, luteal phase defect,hypothyroidism,or any immunological disorder,and infections.have you dr. advised you for lupus anticoagulants and anticardiolipin antibody test.i think you doctor prescribed you right medications. please follow the advice.if thyroid problem is there then your doctor will proper medications.dont worry.take care
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General Surgeon Dr. Swapnendu Sekhar Ghosh's  Response
welcome to healthcaremagic
your statement shows that tsh level is raised means hypo function of thyroid ,a known cause of abortions
your medicine list does not contain thyroid suppement essential to maintain the pregnancy
please consult doctor and thyroid hormone should be started
follow doctor's advice strictly and she should be taking rest and continue treatment till desired outcome
hoping for the best
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  User's Response
Hi Rohit

Welcome to HealthcareMagic.

Recurrent miscarriages is a problem need to be evaluated for Diabetes , Hypothyroidism , APLA syndrome , anatomical problems etc., As her basic tests show no positivity and she is following right treatment to prevent miscarriages , do not worry and advise her to take complete rest and have adequate nutrition with regular medication.These drugs prevent miscarriage.I advise you to get her frequent Obstetrician check up s.

Take care.
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doctor1 MD

History : My sister (Age 32) under gone three repeated miscarriages • First miscarriage happened in 2nd month • Second miscarriage happened in 4th month • Third miscarriage happened in 4th month After third miscarriage we undergone some of the tests suggested by the doctor and below are the details Date : 28 July 2010 Tests undergone first time after three miscarriages Lupus Anticoagulant 1 (Screen) 53 sec (Normal 28-45) Lupus Anticoagulant 2 (confirm) 58 sec (Normal 28-40) Ratio (LA1/LA2) 0.91 ( 1.3 Normal) A.P.T.T TEST 38 sec (result) (Normal 30-40 sec) CONTROL 24 sec (result) (Normal 30-40 sec) ANTI CORDIOLIPIN ANTIBODIES CARDIOLIPIN ANTIBODY – lgM 9.67 PL-lgM-U/mL ( 10 : Negative) CARDIOLIPIN ANTIBODY – lgG 28.0 PL-lgG-U/mL ( 10 : Negative, 10-20 LOW POSITIVE 20-40 MODERATE POSITIVE) CARDIOLIPIN ANTIBODY – lgA 13.27 PL-lgA-U/mL ( 10 : Negative 10-20 LOW POSITIVE) PROLACTIN (PRL) 11.67 ng/ml (Result) (Normal Range ; Females Non-Pregnant: 2.8 – 29.2) Thyroid Stimulating Hormone ( TSH ) 1.06 ulU/mL (Result) (Normal Range 0.34-5.60 ulU/mL) FSH 6.17 mIU/mL (Result) (Normal Range (Normal Range Femal Follicular phase 2.5-10.2) Date : 28 September 2010 After 2 months medication repeated below tests Lupus Anticoagulant 1 (Screen) 32 sec (Normal 28-45) Lupus Anticoagulant 2 (confirm) 36 sec (Normal 28-40) Ratio (LA1/LA2) 0.88 ( 1.3 Normal) A.P.T.T TEST 27 sec (result) (Normal 30-40 sec) CONTROL 24 sec (result) (Normal 30-40 sec) ANTI CORDIOLIPIN ANTIBODIES CARDIOLIPIN ANTIBODY – lgM 8.71 PL-lgM-U/mL ( 10 : Negative) CARDIOLIPIN ANTIBODY – lgG 10.9 PL-lgG-U/mL ( 10 : Negative, 10-20 LOW POSITIVE ) CARDIOLIPIN ANTIBODY – lgA 7.26 PL-lgA-U/mL ( 10 : Negative) Date : 10 January 2011 Found that my sister is affected with TB undergone 6 months course for TB Date : 17 May 2011 Suggested Laproscopic surgery for better findings, after laproscopic surgery below is the discharge summary Recurrent Pregnancy loss for evaluation Operative Hysteroscopy & Laparoscopy done on 17 May 2011 At Hysteroscopy: • Both ostia visualized normally placed • Uterine cavity normal At Laparoscopy: • Uterus normal size • Both tubes normal. Dye test positive both sides. • Small fimbrial cyst present on test tube, excised. • Both overies polycystic, ovarian drilling done • POD free, No E/O adhesions or endometriosis Biopsy result Nature of Specimen: Endometrial Curettings for HPE Microscopic Examination: Sections revealed endometrial tissue with predominantly blood clots and few glands in proliferative pattern. No evidence of neoplasia or granulomas Impression: Proliferative pattern What I want to say: After three miscarriages my sister undergone above tests and some test results were not in normal range, after two months medication those readings came to normal range. And upon our request for any tests Dr. went for Laproscopic surgery and said that she has done ovarian drilling and uterus condition is good and biopsy says that TB which attacked my sister doesn’t have any effect on her uterus. And Dr also says that we need to go Ecosprin and Loprin (not sure of the correct names) injections continously till 9th month once after conceived What I want to ask: There was no specifc finding from Dr that this was the reason for 3 repeated miscarriages, to the best of my knowledge except karotyping we have completed all tests. I am seeking your suggestion in case we are missing any other tests and will be there any side affects of taking daily injections for 9months and any other suggestions/advice are invited. Our whole intension is not to have another miscarriage. Thanks in Advance

doctor1 MD

Hi doctor. My wife is 27 years of age. We got married about 9 months ago. She had a miscarriage in the first few weeks. Now she is pregnant again. Her bhcg is a little lower than usual. She has been prescribed duphaston tabs which she had been taking regularly for the past 10 days or so. What other medicine or injections do you recommend to avoid another miscarriage. Any advice will be highly regarded. Thanks. Salman

doctor1 MD

i am 5-6 weeks pregnant & doctor asked me to take duphaston 10mg twice daily . she said it will help to prevent miscarriages . i am 34 yrs old and conceived after nearly 4 yrs also i do not have a history of miscarriages pls advise whether i should take it?

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