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When Should HCG Injection Given To Result In Pregnancy?
Have pcos I was on clomid 100mg. My follicular size was 10mm on 12th day, 12mm on 14day, 19mm on clomid19th day, 23 on21st day and 25 on 23rd day. For me no injections were prescribed. The result was given as NO EVIDENCE FOR RUPTURE.
Please tell me my ovulating condition and what medication have to be given to me.
Is it effective to give hcg injection if my follicles mature after day16.
Within how many days the follicle have to mature inorder to give hcg injection to result in pregnancy
Please tell me my ovulating condition and what medication have to be given to me.
Is it effective to give hcg injection if my follicles mature after day16.
Within how many days the follicle have to mature inorder to give hcg injection to result in pregnancy
Wed, 12 Feb 2014
Hello and Welcome to ‘Ask A Doctor’ service.
I have reviewed your query and here is my advice.
You seem to develop follicles but they do not rupture due to PCOS. HCG can be used to help in rupturing follicles. Usually it is given at follicle size 16 mm and above. If it is reaching this size in more than 16 days, try a higher dose of clomid, or combine it with letroz or sildenafil, depending upon the condition of endometrium.
Metformin can also be used for PCOS after discussing with your infertility specialist. There is no clear limit on when follicle should mature. Also the ovulation study was done on day 14 and then 19. A gap of 4 days at peak follicle size is not advisable and it needs to be done more frequently to detect a 14-16 mm follicle.
Try this for 1 or 2 cycles only, preferably with IUI for best results. Repeated use of clomid makes the endometrium weak and it cannot receive a fertilized ovum hampering pregnancy even if there is ovulation.
If there is no response then laparoscopic drilling offers best solutions and maximum chances of conception in the next few cycles post drilling.
Hope I have answered your query. Let me know if I can assist you further.
Regards,
Dr. Madhuri N Bagde
I have reviewed your query and here is my advice.
You seem to develop follicles but they do not rupture due to PCOS. HCG can be used to help in rupturing follicles. Usually it is given at follicle size 16 mm and above. If it is reaching this size in more than 16 days, try a higher dose of clomid, or combine it with letroz or sildenafil, depending upon the condition of endometrium.
Metformin can also be used for PCOS after discussing with your infertility specialist. There is no clear limit on when follicle should mature. Also the ovulation study was done on day 14 and then 19. A gap of 4 days at peak follicle size is not advisable and it needs to be done more frequently to detect a 14-16 mm follicle.
Try this for 1 or 2 cycles only, preferably with IUI for best results. Repeated use of clomid makes the endometrium weak and it cannot receive a fertilized ovum hampering pregnancy even if there is ovulation.
If there is no response then laparoscopic drilling offers best solutions and maximum chances of conception in the next few cycles post drilling.
Hope I have answered your query. Let me know if I can assist you further.
Regards,
Dr. Madhuri N Bagde
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