Hi. Thanks for posting your concern at HCM Fungal infection of the groin/jock itch develops due to conducive environment provided by the body folds. Sweating, humidity, obesity are factors that encourage fungal growth. Lotrimin cream contains clotrimazole which is a topical antifungal. Sometimes topical antifungal alone is ineffective. You need to add an oral antifungal in addition to the topical antifungal. I would recommend either a plain antifungal like clotrimazole(Candid cream)/Ketoconazole/sertaconazole(Onabet cream)/luliconazole etc OR an antifungal+steroid combination cream e.g clotrimazole+beclomethasone cream(Candid-B Cream/Canesten-B cream) or Sertaconazole+beclomethasone (Onabet-B cream). In my practice i also prescribe an oral antifungal along with the topical cream e.g Fluconazole 150mg tablet to be taken once every week for 4-6 weeks An OTC antihistamine e.g cetrizine or loratadine can be taken once or twice daily for symptomatic itch relief. Once the infection gets cured I advice my patients to use an antifungal dusting powder twice daily. It keeps the area dry and being antifungal it does nt allow the fungus to proliferate again.