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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What causes fever with swollen lymph nodes?

What could be the cause of a 2 yr old running a fever, with no other symptoms, and very swollen lymphnodes? He s has numerous blood work and things like his red blood cell count is 15.3 (high), Neutrophils are 13 (low), Lymphs 72 (high) with smudge cells present, Monocytes 11 (high) and Neutrophils-Absolute at 0.9 (low). He s scheduled for a doctor s appt today, I would like to know what types of questions (or answers) I should ask or expect because he s been sick since Thanksgiving and they just keep taking more blood and not really giving me an answer, other than it s viral, as to why he s not getting better.
Fri, 23 Jun 2017
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Pediatrician 's  Response
Most common cause of lymph node swelling is infection by virus, bacteria or fungi in the area which drains into that lymph node. Other causes may be injury, cancer, immunological disorders, lymphomas etc.
General swelling of lymph nodes throughout body may indicate an infection, such as HIV or mononucleosis, or an immune disorder, such as lupus or rheumatoid arthritis.
The Smudge cells present in blood may be 0.01% in severe infection of may be up to 20 % in lymphocytic leukemia.
High lymphocytes, low neutrophils, and high monocytes counts may be elevated in infectious mononucleosis, infection, certain bacterial infection like TB, typhoid etc.

CONCLUSION:
As per information provided, you child is probably suffering from viral infection. Ask your doctor for further investigation like lymph node biopsy (FNAC), PCR for EBV, Widal, PS examination by pathologist, blood culture etc. to confirm diagnosis.
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What causes fever with swollen lymph nodes?

Most common cause of lymph node swelling is infection by virus, bacteria or fungi in the area which drains into that lymph node. Other causes may be injury, cancer, immunological disorders, lymphomas etc. General swelling of lymph nodes throughout body may indicate an infection, such as HIV or mononucleosis, or an immune disorder, such as lupus or rheumatoid arthritis. The Smudge cells present in blood may be 0.01% in severe infection of may be up to 20 % in lymphocytic leukemia. High lymphocytes, low neutrophils, and high monocytes counts may be elevated in infectious mononucleosis, infection, certain bacterial infection like TB, typhoid etc. CONCLUSION: As per information provided, you child is probably suffering from viral infection. Ask your doctor for further investigation like lymph node biopsy (FNAC), PCR for EBV, Widal, PS examination by pathologist, blood culture etc. to confirm diagnosis.