Hi, Calvepen (penicillin V) is an antibiotic medication used to treat bacterial infections such as strep throat, tonsillitis, and skin infections. It works by stopping the growth of bacteria in the body, allowing the immune system to fight off the infection. Prednisolone steroid is used to reduce any bodily inflammation. It is commonly prescribed to treat conditions such as asthma, rheumatoid arthritis, and allergic reactions. In your case, your doctor likely prescribed prednisolone to help reduce the swelling in your glands and throat, which is causing your discomfort. As for the fact that you have had your tonsils removed, this may make a difference in the types of infections you are susceptible to. Tonsillitis is an infection of the tonsils, and without them, you may be less likely to develop this particular infection. However, you can still develop other types of infections, and your doctor will prescribe appropriate treatment based on your symptoms and medical history. It is important to follow your doctor s instructions and complete the full course of antibiotics and steroids to ensure that the infection is fully treated. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Priyanka, General & Family Physician