You have not described your symptoms fully. Parenchymal disease means that the organ specific tissue is diseased- it can be of the kidneys, lung, liver, heart or any organ of the body. From your description, it is apparent that you are having multiorgan involvement for which there are many causes. Are you also suffering from high BP or diabetes? Have you been running low grade fever, have cough or joint pains? You should consult a physician and get yourself thoroughly investigated to establish the diagnosis with special emphasis on ruling out kidney, heart and liver problem or chronic infection like disseminated TB or a connective tissue disorder..