Hi there ~ I understand your concerns. Having the habit of smoking cannabis might alter the way in which your body responds to prescription medications, i.e. rexipra and depran. Although there are no drug interactions reported, the psychological effects caused by the cannabis may affect the experience you have from your antidepressants. However, there are no withdrawal symptoms reported from cannabis. If your ECG, thyroid test and echo test are normal, I advise you to stop smoking the cannabis as you are at an early stage where you habit may have not reached the stage of dependence and your health may be salvageable in the long term. For the nervous feelings, please consult your psychiatrist as there may be a medication that could be prescribed. I hope this helps. Take care of yourself and have a lovely day!