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Taken adderall, Having having an endoscopy to stretch my esophagus. Is taking adderall before anesthesia is bad?

I took adderall about 17 1/2 hours before my procedure (which is tomorrow morning). Its is a 20 mg instant and tomorrow I am having an endoscopy to stretch my esophagus due to a narrowing. They are going to put me under a twilight sleep so it isn t 100% sleep. Are there severe dangers with that or am I safe? I know taking adderall before anesthesia is bad and I should consult the doctor and all anesthesia comes with risks but on a scale of 1-10, how much of a risk does that present for severe complications for the max 15 minute procedure?
Asked On : Mon, 25 Jun 2012
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General & Family Physician 's  Response
Hi, thanks for asking in Healthcare Magic.

Adderall contains a mixture of Amphetamine amphetamine and Dextro-amphetamine. It is a mood elevator and also is given in Attention deficit disorder.

Flourinated General anesthetics like Halothane, Enflurane and methoxyflurane interact with Amphetamine by sensitizing heart to the effects of Amphetamine which can result in arrhythmia. These drugs are called general anesthetics as they result in reversible loss of conciousness.

But you have mentioned that it is going to be a 'twilight sleep' which means "Dissociative Anesthesia" or "Conscious Sedation", characterized by profound analgesia, light sleep and a feeling of dissociation. The drug Ketamine is given to induce dissociative anesthesia. This does not interact with Adderall.

You have taken Adderall 20 mg, 17 hours before surgery. It is not the toxic dose.The elimination half life (time taken for the drug to be excreted completely from body) of Amphetamine is 20 hours and that of Dextroamphetamine is 11 hours. So nearly 90% of Adderall would have been eliminated before anesthesia.

Acidification of urine with ammonium chloride will increase the excretion of Amphetamine and Dextroamphetamine and are given in overdose of these drugs to eliminate them completely from the body. Otherwise you can take some fruit juices which also will acidify the urine and will help in elimination of Adderall from your system

I hope this is useful to you.
Answered: Thu, 11 Apr 2013
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