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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Sinus Infection, Hives And Itching, Tiredness. Was On Sulfamethoxazole And Benadryl. What Is Wrong?

Hi, may I answer your health queries? Please type your query here... I was one sulfamethoxazole for a sinus infection a month ago i did not finish the 10 days. I felt like i was getting my sinus infection back so I took a pill and about an hour later got very itchy hives all over! i took benedryl and now thinking after if that was ok to mix the 2. 2 1/2 hours later the hives have stopped itching. But feel very very tired. I am hoping it was ok to interact the 2 drugs.. Now i am so tired I could go to bed. Is that ok to feel this way
Thu, 25 Jul 2013
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General & Family Physician,  's  Response
Hello,
Thanks for the query to H.CM. Forum.
Sulfa drugs are most potent and it causes reaction .
As you mentioned that you took this tablet after a gap and develops itch & hives.
May be due to allergy ( reaction) of drug or due to allergic sinusitis.
As you got benedrl ( antihistamine ) & relief means both possibilities are there.
Anyhow , now you are symptom free so need not to worry.
Tiredness may be due to both above mentioned reason .
Get 1-2 tablets of painkiller and you will get relief.
Good luck.
Dr. HET
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Sinus Infection, Hives And Itching, Tiredness. Was On Sulfamethoxazole And Benadryl. What Is Wrong?

Hello, Thanks for the query to H.CM. Forum. Sulfa drugs are most potent and it causes reaction . As you mentioned that you took this tablet after a gap and develops itch & hives. May be due to allergy ( reaction) of drug or due to allergic sinusitis. As you got benedrl ( antihistamine ) & relief means both possibilities are there. Anyhow , now you are symptom free so need not to worry. Tiredness may be due to both above mentioned reason . Get 1-2 tablets of painkiller and you will get relief. Good luck. Dr. HET